Session / Events

Updated on October 1, 2012

Note that the order/session of speakers may change according to their topics. Please watch out for the latest update.

Symposium topics and speakers

■ November 7th (Wed)

1. Kisspeptin neuron development and puberty [8:30 ~ 10:30 A.M.]

Chair:

Nicolas de Roux

Speakers

  • ・Alexander S. Kauffman (USA): Developmental Regulation of Kisspeptin Neurons in Rodents
  • ・Isabelle Franceschini (France): Kisspeptins in the Embryonic and Early Postnatal Brain
  • ・Ulrich Boehm (Germany): Kisspeptin Neurons and the Onset of Puberty
  • ・Ei Terasawa (USA): Role of Kisspeptin Signaling in Puberty Onset and Pubertal Development

2. Regulation of kisspeptin neurons: Epigenetic/hormonal [2:30 ~ 3:30 P.M.]

Chair:

Manuel Tena-Sempere

Speakers

  • ・Hiroko Tsukamura (Japan): Epigenetic Regulation of Kiss1 Gene Expression Mediating Estrogen Positive Feedback Action
  • ・Sue Moenter (USA): Hormonal Control of Kisspeptin Neurons

3. Molecular and biophysical/electrophysiological properties of kisspeptin neurons [4:00 ~ 5:30 P.M.]

Chair:

Yoshitaka Oka

Speakers

  • ・Meenakshi Alreja (USA) : Neuropeptide Regulation of Kisspeptin Neurons
  • ・Allan Herbison (NZ): Electrical Firing Properties of Arcuate and Preoptic Kisspeptin Neurons in the Mouse.
  • ・Martin Kelly (USA) : Pacemaker Activity of Kisspeptin Neurons

■ November 8th (Thu)

4. Role of arcuate KNDy neurons in GnRH pulse generation [8:30 ~ 12:00 A.M.]

4-1 [8:30 ~ 10:00 A.M.]

Chair:

Robert Steiner

Speakers

  • ・Michael Lehman (USA): KNDy Cells: Testing Their Role in the GnRH Pulse Generator and Beyond
  • ・Yoshihiro Wakabayashi (Japan): A Possible Mechanism for GnRH Pulse Generation by KNDy Neurons.
  • ・Victor Navarro (USA): KNDy Neurons as Pacemakers of GnRH Secretion: A Role in Initiating and Maintaining Reproduction

4-2 [10:30 ~ 12:00 A.M.]

Chair:

Ei Terasawa

Speakers

  • ・Kevin O’Byrne (UK) : KNDy Neuropeptide Interactions and Pulsatile LH Secretion.
  • ・Naomi Rance (USA): Effects of KNDy Neuron Ablation on the Estradiol Modulation of LH Secretion, Body Weight and Thermoregulation
  • ・Berta Levavi-Sivan (Israel): Neurokinin B/NKB Receptor System is Involved in the Control of Fish Reproduction

5. Diversity of Kisspeptin/GPR54 systems [4:00 ~ 5:30 P.M.]

Chair:

Bill Colledge

Speakers

  • ・Olivier Kah (France): Two Kisses for One Fish
  • ・Alain Caraty (France): Kisspeptin Isoforms in the Hypothalamus: What's New
  • ・ Ishwar Parhar (Malaysia): Independent Functions of the Two Kisspeptin Systems in Fish

■ November 9th (Fri)

6. Regulation of kisspeptin neurons: Metabolic/lactational [8:30 ~ 10:00 A.M.]

Chair:

Alexander S. Kauffmann

Speakers

  • ・Manuel Tena-Sempere (Spain): Metabolic Control of Kisspeptin Signaling: Interactive Partners and Molecular Mechanisms
  • ・Carol Elias (USA): Direct Action of Metabolic Cues on Kiss1 Neurons: Complexity or Redundancy?
  • ・Susan Smith (USA): CART Neurons as Potential Mediators of Kisspeptin and GnRH Inhibition during Negative Energy Balance

7. Regulation of kisspeptin neurons: Seasonal/photoperiodic/circadian [10:30 ~ 12:00 A.M.]

Chair:

Iain Clarke

Speakers

  • ・Jeremy Smith (Australia): Kisspeptin and Seasonal Reproduction: What's the Link?
  • ・Robert Goodman (USA) : Comparison of the Role of Kisspeptin in Three Seasonally Breeding Mammals
  • ・Lance Kriegsfeld (USA) : Kisspeptin as a Key Node in the Circadian Network Driving Female Reproduction

8. Kisspeptin in clinical therapies/human genetic [4:00 ~ 6:00 P.M.]

Chair:

Tetsuya Ohtaki

Speakers

  • ・Nicolas de Roux (France): Molecular Genetics of Kisspeptin/KISS1R and Ontogenesis in Humans
  • ・Erik Hrabovszky (Hungary): Sexual Dimorphism and Aging-Dependent Neuroanatomical Changes of the Human Kisspeptin and Neurokinin B Systems
  • ・Robert Millar (UK) : The Role of Kisspeptin in GnRH Pulsatility: Insights from Clinical and Animal Studies
  • ・Stephanie Seminara (USA) : Kisspeptin: a Window into GnRH Neuronal Function

Oral Sessions

1. Oral Session 1 / November 7th, 11:00 A.M.-12:30 P.M. [O-1.1 ~ O-1.6]

Chair:

Yoshihisa Uenoyama

2. Oral Session 2 / November 8th, 2:00 P.M.-3:30 P.M. [O-2.1 ~ O-2.6]

Chair:

Hiroaki Okamura

3. Oral Session 3 / November 9th, 2:00 P.M.-3:30 P.M. [O-3.1 ~ O-3.6]

Chair:

Hiroko Tsukamura

Special topic forums with dinner

(November 7th, 6:00~8:00 P.M.)

・Transgenics/knock-ins and controversies: fleshing out their strengths, limitations, caveats

Chair: Robert Steiner (U Washington),Stephanie Seminara (MGH), William Colledge (U Cambridge)

Public Lectures

(November 6th 4:00~5:30)

Chair: Kei-Ichiro Maeda

・Stephanie Seminara (MGH) : Where have We been and Where are We Going?

・Allan Herbison (U Otago): Kisspeptin neurobiology; the GnRH neuron and beyond

Luncheon seminar

(November 9th 12:15~01:00PM, 20 min talk for each)

Chair: Nicolas de Roux (Robert Debré Hospital)

・Hitoshi Ozawa (Nippon Medical Sch): The Interaction of the Reproductive Regulation, Energy Metabolic Regulation and Stress Response through Kisspeptin Signaling System

・Hisanori Matsui (Takeda Pharmaceutical Inc): Testosterone Depletion by Continuous Administration of Kisspeptin Analogues