Recent publications (1995-2020)

Updated 3/5/2020

Neurobiology

Kayo D, Oka Y, Kanda S (2020) Examination of methods for manipulating serum 17ƒΐ-Estradiol (E2) levels by analysis of blood E2 concentration in medaka (Oryzias latipes). General and Comparative Endocrinology 285: 113272. https://doi.org/10.1016/j.ygcen.2019.113272

Kayo D, Zempo B, Tomihara S, Oka Y, Kanda S (2019) Gene knockout analysis reveals essentiality of estrogen receptor ?1 (Esr2a) for female reproduction in medaka. Scientific Reports, https://doi.org/10.1038/s41598-019-45373-y.

Kikuchi Y, Hiraki-Kajiyama T, Nakajo M, Umatani C, Kanda S, Oka Y, Matsumoto K, Ozawa H, Okubo K (2019) Sexually dimorphic neuropeptide B neurons exhibit activated cellular phenotypes dependent on estrogen. Endocrinology 160:827?839. doi: 10.1210/en.2019-00030.

Umatani C, Oka Y (2018) Juvenile-specific burst firing of terminal nerve GnRH3 neurons suggests novel functions in addition to neuromodulation. Endocrinology 2018 Apr 1;159(4):1678-1689. doi: 10.1210/en.2017-03210

Zempo B, Karigo T, Kanda S, Akazome Y, Oka Y (2018) Morphological Analysis of the Axonal Projections of EGFP-Labeled Esr1-Expressing Neurons in Transgenic Female Medaka. Endocrinology 159:1228-1241. doi:10.1210/en.2017-00873

Nakajo M, Kanda S, Karigo T, Takahashi A, Akazome Y, Uenoyama Y, Kobayashi M, Oka Y@(2018) Evolutionally conserved function of kisspeptin neuronal system is non-reproductive regulation: novel perspectives from non-mammal study. Endocrinology 159:163-183.doi: 10.1210/en.2017-00808

Hasebe M, Oka Y (2017) High-frequency firing activity of GnRH1 neurons in female medaka induces the release of GnRH1 peptide from their nerve terminals in the pituitary. Endocrinology 158: 2603-2617. doi: 10.1210/en.2017-00289

Hasebe M, Kanda S, Oka Y (2016) Female specific glucose-sensitivity of GnRH1 neurons leads to sexually dimorphic inhibition of reproduction in medaka. Endocrinology, doi: 10.1210/en.2016-1352

Takahashi A, Kanda S, Abe T, Oka Y (2016) Evolution of the hypothalamic-pituitary-gonadal axis regulation in vertebrates revealed by knockout medaka. Endocrinology, doi: 10.1210/en.2016-1356

Takahashi A, Islam MS, Abe H, Okubo K, Akazome Y, Kaneko T, Hioki H, Oka Y (2016)  Morphological analysis of the early development of telencephalic and diencephalic gonadotropin-releasing hormone neuronal systems in the enhanced green fluorescent protein-expressing transgenic medaka lines.
Journal of Comparative Neurology 524:896-913. doi: 10.1002/cne.23883.

Kanda S, Oka Y (2015) Kisspeptin. Handbook of Hormones. eds. Takei Y, Ando H, Tsutsui K. Elevier/Academic Press, Subchapter 1B: pp. 10-13.

Umatani C, Misu R, Oishi S, Yamaguchi K, Abe H, Oka Y (2015) GnRH suppresses excitability of visual-processing neurons in the optic tectum. J. Neurophysiology 114: 2775-2784. doi: 10.1152/jn.00710.2015


Kawai T, Yoshimura A, Oka Y (2015) Neurons in the preoptic area of the male goldfish are activated by a primer pheromone 17ƒΏ,20ƒΐ-dihydroxy-4-pregnen-3-one. Journal of Neuroendocrinology 27: 123-130. doi: 10.1111/jne.12243

Williams BL, Akazome Y, Oka Y, Eisthen HL (2014) Dynamic evolution of the GnRH receptor gene family in vertebrates. BMC Evolutionary Biology.

Hasebe M*, Kanda S*, Shimada H, Akazome Y, Abe H, Oka Y (*: equal contribution) (2014) Kiss1 neurons drastically change their firing activity in accordance with the reproductive state: insights from a seasonal breeder. Endocrinology 155: 4868?4880. doi:10.1210/en.2014-1472

Maehiro S, Takeuchi A, Yamashita J, Hiraki T, Kawabata Y, Nakasone K, Hosono K, Usami T, Paul-Prasanth B, Nagahama Y, Oka Y, Okubo K (2014) Sexually dimorphic expression of the sex chromosome-linked genes cntfa and pdlima in the medaka brain. Biochemical and Biophysical Research Communications 445:113-119. doi: 10.1016/j.bbrc.2014.01.131. Epub 2014 Jan 31.

Karigo T, Aikawa M, Kondo C, Abe H, Kanda S, Oka Y (2014) Whole brain-pituitary in vitro preparation of the transgenic medaka (Oryzias latipes) as a tool for analyzing the differential regulatory mechanisms of LH and FSH release. Endocrinology doi:10.1210/en.2013-1642

Okuyama T, Yokoi S, Abe H, Isoe Y, Suehiro Y, Imada H, Tanaka M, Kawasaki T, Yuba S, Taniguchi Y, Kamei Y, Okubo K, Shimada A, Naruse K, Takeda H, Oka Y, Kubo T, Takeuchi H (2014) A neural mechanism underlying mating preferences for familiar individuals in medaka fish. Science 343, 91-94. doi: 10.1126/science.1244724.

Karigo T, Oka Y (2013) Neurobiological study of fish brains gives insights into the nature of gonadotropin-releasing hormone 1-3 neurons. Frontiers in Endocrinology (Experimental Endocrinology). gBiology of Gonadotropin-Releasing Hormone Neuronsh 19 November 2013 | doi: 10.3389/fendo.2013.00177

Kanda S, Oka Y (2013) Structure, synthesis, and phylogeny of kisspeptin and its receptor. In: gKisspeptin Signaling in Reproductive Biologyh (ed. by A. Kauffman and J. Smith), Chapter 2, Springer Verlag, New York, pp. 9-26.@Adv Exp Med Biol. 2013;784:9-26. doi: 10.1007/978-1-4614-6199-9_2 

Kawai T, Abe H, Oka Y (2013). Burst generation mediated by cholinergic input in terminal nerve-gonadotrophin releasing hormone neurones of the goldfish. Journal of Physiology-London 591: 5509-5523. doi:10.1113/jphysiol.2013.258343.

Hodne K, Weltzien FA, Oka Y, Okubo K (2013) Expression and putative function of kisspeptins and their receptors during early development in medaka. Endocrinology 154: 3437-3446. doi:10.1210/en.2013-1065

Kanda S, Akazome Y, Mitani Y, Okubo K, Oka Y (2013) Neuroanatomical evidence that kisspeptin directly regulates isotocin and vasotocin neurons. PLosOne 8: e62776. doi:10.1371/journal.pone.0062776

Umatani C, Abe H, Oka Y (2013) Neuropeptide RFRP inhibits the pacemaker activity of terminal nerve GnRH neurons. Journal of Neurophysiology 109: 2354-2363. doi:10.1152/jn.00145.2012.

Zempo B, Kanda S, Okubo K, Akazome Y, Oka Y (2013) Anatomical distribution of sex steroid hormone receptors in the brain of female medaka.  Journal of Comparative Neurology 521: 1760-1780. doi: 10.1002/cne.23255.

Kanda S, Oka Y (2012) Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain. Frontiers in Genomic Endocrinology "Estrogenic control of hypothalamic GnRH neurons" 3:28. doi: 10.3389/fendo.2012.00028.

Hiraki T, Takeuchi A, Tsumaki T, Zempo B, Kanda S, Oka Y, Nagahama Y, Okubo K (2012) Female-specific target sites for both estrogen and androgen in the teleost brain. Proceedings of the Royal Society. B, Biological sciences 279: 5014-5023. doi: 10.1098/rspb.2012.2011.

Karigo T, Kanda S, Abe H, Okubo K, Oka Y (2012) Time-of-day dependent changes in GnRH1 neuronal activities and gonadotropin mRNA expression in a daily spawning fish, medaka. Endocrinology 153: 3394-3404. doi: 10.1210/en.2011-2022. Epub 2012 Apr 27.

Kanda S, Karigo T, Oka Y (2012) Steroid sensitive kiss2 neurones in the goldfish: evolutionary insights into the duplicate kisspeptin gene-expressing neurones. Journal of Neuroendocrinology 24:897-906.

Kawai T, Abe H, Oka Y (2012) Dopaminergic neuromodulation of synaptic transmission between the mitral and granule cells in the teleost olfactory bulb. Journal of Neurophysiology 107: 1313-1324.

Abe H, Oka Y (2011) Mechanisms of neuromodulation by a non-hypophysiotropic GnRH system controlling motivation for reproductive behavior in the teleost brain. Journal of Reproduction and Development 57: 665-674

Shimizu Y, Tomikawa J, Hirano K, Nanikawa Y, Akazome Y, Kanda S, Kazeto Y, Okuzawa K, Uenoyama Y, Ohkura S, Tsukamura H, Maeda K, Gen K, Oka Y, Yamamoto N (2011) Central distribution of kiss2 neurons and peri-pubertal changes in their expression in the brain of the male and female red seabream Pagrus major. General and Comparative Endocrinology 175: 432-442.

Amiya N, Amano M, Tabuchi A, Oka Y (2011) Anatomical relations between neuropeptide Y, galanin, and gonadotropin-releasing hormone in the brain of chondrostean, the Siberian sturgeon Acipenser baeri. Neuroscience Letters 503F87-92.

Kanda S, Okubo K, Oka Y (2011) Differential regulation of luteinizing hormone genes in teleosts and tetrapods due to their distinct genomic environments?insights into gonadotropin beta subunit evolution. General and Comparative Endocrinology 173: 253-258.

Akazome Y, Kanda S, Oka Y (2011) Expression of vesicular glutamate transporter-2.1 in medaka terminal nerve gonadotrophin-releasing hormone neurones. Journal of Neuroendocrinology 23: 570-576.

Okubo K, Takeuchi A, Chaube R, Paul-Prasanth B, Kanda S, Oka Y, Nagahama Y@(2011) Sex differences in aromatase gene expression in the medaka brain. Journal of Neuroendocrinology 23: 412-423

Maeda K, Ohkura S, Uenoyama Y, Wakabayashi Y, Oka Y, Tsukamura H, Okamura H (2010) Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus. Brain Research 1364 (Review, Special Issue: New Insights into the Neurobiology of Reproduction and Puberty): 103-115.

Kanda S, Oka Y (2010) Transgenic medaka in neurobiological studies. Laboratory Animal Technology and Science. 22(5): 16-22.

Oka Y (2010) Electrophysiological characterization of GnRH1-3 neuronses: insights from a study of fish brains. Journal of Neuroendocrinology 22: 659-663.

Akazome Y, Kanda S, Okubo K, Oka Y (2010) Functional and evolutionary insights into vertebrate kisspeptin systems from studies of fish brain. Special Issue of the Journal of Fish Biology; Reproductive Physiology STATE-OF-THE-SCIENCE, Journal of Fish Biology 76: 161-182

Kawai T, Abe H, Akazome Y, Oka Y (2010) Neuromodulatory effect of GnRH on the synaptic transmission of the olfactory bulbar neural circuit in goldfish, Carassius auratus. Journal of Neurophysiology 104: 3540-3550.

Saito* T, Nakane* R, Akazome Y, Abe H, Oka Y (2010) Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons. (*: equal contribution) Journal of Neurophysiology 104: 3518-3529.

Amano M, Yokoyama T, Amiya N, Hotta M, Takakusaki Y, Kado R, Oka, Y (2010) Biochemical and immunohistochemical analyses of GnRH-like peptides in the nerve ganglion of the chiton, Acanthopleura japonica. Zoological Science 27: 924-930.

Amano M, Moriyama S, Okubo K, Nagai Y, Amiya N, Takahashi A, Oka Y (2010) Biochemical and immunohistochemical analyses of a GnRH-like peptide in the neural ganglia of the Pacific abalone Haliotis discus hannai (Gastropoda). Zoological Science 27: 656-661.

Nakane R, Oka Y (2010) Excitatory action of GABA in the terminal nerve gonadotropin-releasing hormone neurons. Journal of Neurophysiology 103: 1375-1384

Mitani* Y, Kanda* S, Akazome Y, Zempo B, Oka Y (2010) Hypothalamic kiss1 but not kiss2 neurons are involved in estrogen feedback in medaka (Oryzias latipes) *: equal contribution Endocrinology 151: 1751-1759

Kanda* S, Nishikawa* K, Karigo T, Okubo K, Isomae S, Abe H, Kobayashi D, Oka Y (2010) Regular pacemaker activity characterizes gonadotropin-releasing hormone 2 neurons recorded from green fluorescent protein-transgenic medaka. *: equal contribution Endocrinology 151: 695-701

Oka Y (2009) Physiological properties of neuroendocrine and neuromodulatory GnRH peptidergic neurons. Tsukuba Brain Science Seminar Abstracts Vol. 7: 13.

Kawai T, Oka Y, Eisthen H (2009) The role of the terminal nerve and GnRH in olfactory system neuromodulation. Zoological Science 26:669-680

Oka Y (2009) Three types of gonadotrophin-releasing hormone neurones and steroid-sensitive sexually dimorphic kisspeptin neurones in teleosts. Journal of Neuroendocrinology 21: 334-338.

Amano M, Okumura T, Okubo K, Amiya N, Takahashi A, Oka Y (2009) Biochemical analysis and immunohistochemical examination of a GnRH-like immunoreactive peptide in the central nervous system of the decapod crustacean the kuruma prawn Marsupenaeus japonicus. Zoological Science 26: 840-845.

Kawai T, Abe H, Wakabayashi K, Oka Y (2009) Calcium oscillations in the olfactory nonsensory cells of the goldfish, Carassius auratus. Biochimica et Biophysica Acta-General Subjects 1790: 1681-1688.

Amano M, Amiya N, Hiramatsu M, Oka Y (2009) Interaction between neuropeptide Y immunoreactive neurons and galanin immunoreactive neurons in the brain of the masu salmon, Oncorhynchus masou. Neuroscience Letters 462:33-38

Takase K, Uenoyama Y, Inoue N, Matsui H, Yamada S, Shimizu M, HommaT, Tomikawa J, Kanda S, Matsumoto H, Oka Y, Tsukamura H, Maeda KI (2009) Possible role of oestrogen in pubertal increase of Kiss1/Kisspeptin expression in discrete hypothalamic areas of female rats. Journal of Neuroendocrinology 21:527-537

Abe H, Oka Y (2009) Primary culture of the isolated terminal nerve-gonadotropin releasing hormone (GnRH) neurons derived from adult teleost (dwarf gourami, Colisa lalia) brain for the study of peptide release mechanisms. Journal of Neuroendocrinology 21:489-505

Kato K, Oka Y, Park MK (2008) Identification and expression analysis of peroxisome proliferator-activated receptors cDNA in a reptile, the leopard gecko (Eublepharis macularius). Zoological Science 25: 492-502.

Amano M, Oka Y, Nagai Y, Amiya N, Yamamori K (2008) Immunohistochemical localization of a GnRH-like peptide in the brain of the cephalopod spear-squid, Loligo bleekeri. General and Comparative Endocrinol. 156: 277-284.

Haneda K, Oka Y (2008) Coordinated synchronization in the electrically coupled network of terminal nerve gonadotropin-releasing hormone neurons as demonstrated by double patch-clamp study. Endocrinology 149:3540-3548.

Kanda S, Akazome Y, Yamamoto N, Yamada S, Tsukamura H, Maeda K, Oka Y (2008) Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually-dimorphic kisspeptin neurons in medaka (Oryzias latipes). Endocrinology 149: 2467-2476.

Abe H, Keen KL, Terasawa E (2008) Rapid action of estrogens on intracellular calcium oscillations in primate luteinizing hormone-releasing hormone-1 neurons. Endocrinology 149(3):1155-62.

Hajdu P, Ikemoto T, Akazome Y, Park MK, Oka Y (2007) Terminal nerve GnRH neurons express multiple GnRH receptors in a teleost, the dwarf gourami (Colisa lalia). Journal of Neuroendocrinology 19: 475-479.

Amano M, Oka Y, Amiya N,Yamamori K (2007) Immunohistochemical localization and ontogenic development of prolactin-releasing peptide in the brain of the ovoviviparous fish species Poecilia reticulata (guppy). Neuroscience Letters 413: 206-209.

Amiya N, Amano M, Oka Y, Iigo M, Takahashi A, Yamamori K (2007) Immunohistochemical localization of orexin/hypocretin-like immunoreactive peptides in the brain and pituitary of medaka. Neuroscience Letters 427: 16-21.

Tanaka H, Oka Y (2007) Hofmeister effect underlying the quiescence of sperm motility in the vas deferens of the viviparous guppy Poecilia reticulata. Zoological Science 24: 1259-1265.

Abe H, Oka Y (2007) Neuromodulatory functions of terminal nerve-GnRH neurons. In : gFish Physiology Vol. 25, Sensory Systems Neuroscienceh (ed. By T.J. Hara and B. Zielenski), Chapter 11, Elsevier Inc., San Diego, pp. 455-503.

Oka Y (2007) Mechanisms of neuronal and endocrine systems that enable adaptive behaviors in vertebrates. In: "Zoological Sciences in 21st Century Vol. 8, Animal Behavior and Communication" (ed. By Y. Oka and K. Arikawa), Chapter 8, Baifu-kan, Tokyo, pp. 197-226 (In Japanese).

Oka Y (2007) Diversity of animal behavior and communication. In: "Zoological Sciences in 21st Century Vol. 8, Animal Behavior and Communication" (ed. By Y. Oka and K. Arikawa), Chapter 8, Baifu-kan, Tokyo, pp. 1-7 (In Japanese).

Tsutsui H, Oka Y (2007) Ion channels and their neural functions: contribution to general problems from studies of brains in non-mammalian species. Brain, Behavior and Evolution 69: 122-131.

Tsutsui H, Oka Y (2005) Non-typical Na+ channels and neural functions. Seitai no Kagaku 56: 181-189 (In Japanese).

Abe H, Terasawa E (2005) Firing pattern and rapid modulation of activity by estrogen in primate luteinizing hormone releasing hormone-1 neurons. Endocrinol. 146: 4312-4320.

Amano M, Takahashi A, Yamanome T, Oka Y, Amiya N, Kawauchi H, Yamamori K (2005) Immunocytochemical localization and ontogenic development of ƒΏ-melanocyte-stimulating hormone (ƒΏ-MSH) in the brain of pleuronectiform fish, Barfin Flounder. Cell and Tissue Research 320: 127 - 134

Tanaka H, Oka Y (2005) Chaotropes and multi-valent cations activate guppy sperm motility. Biochimica et Biophysica Acta-General Subjects 1724: 173-180.

Haneda K, Oka Y (2004) Selective modulation of voltage-gated calcium channels in the terminal nerve gonadotropin-releasing hormone (TN-GnRH) neurons of a teleost, the dwarf gourami (Colisa lalia). Endocrinology 145: 4489-4499.

Ishizaki M, Iigo M, Amano M, Oka Y (2004) Different modes of gonadotropin-releasing hormone (GnRH) release from multiple GnRH systems as revealed by radioimmunoassay using brain slices of a teleost, the dwarf gourami (Colisa lalia). Endocrinology 145: 2092-2103.

Ishikawa M, Tsutsui H, Cosson J, Oka Y, Morisawa M (2004) Strategies for sperm chemotaxis in the siphonophores and ascidians: a numerical simulation study. Biological Bulletin 206: 95-102.

Amano M, Okubo K, Yamanome T, Oka Y, Kawaguchi N, Aida K, Yamamori K (2004) Ontogenic development of three GnRH systems in the brain of a pleuronectiform fish, barfin flounder. Zoological Science 21: 311-317.

Tateyama M, Abe H, Nakata H, Saito O, Kubo Y (2004) Ligand-induced dynamic rearrangement of the intracellular dimeric conformation of metabotropic glutamate receptor1a. Nat. Struct. & Mol. Biol. 11: 637-642.

Kiya T, Oka Y (2003) Glutamate receptors in the terminal nerve gonadotropin-releasing hormone neurons of the dwarf gourami (teleost). Neuroscience Letters 345: 113-116.

Amano M, Oka Y, Yamanome T, Takahashi A, Yamamori K (2003) Immunocytochemical localization and ontogenic development of melanin-concentrating hormone in the brain of a pleuronectiform fish, the barfin flounder. Cell and Tissue Research 311: 71-77.

Amano M, Okubo K, Yamanome T, Oka Y, Kitamura S, Ikuta K, Takahashi A, Aida K, Yamamori K (2003) GnRH systems in masu salmon and barfin flounder. Fish Physiology and Biochemistry 28: 19-22.

Oka Y (2002) What are the functional roles of non-hormonal peptides in the brain? Comparative Physiology and Biochemistry 19: 120-127 (In Japanese).

Oka Y (2002) Physiology and release activity of GnRH neurons. Progress in Brain Research 141: 259-281.

Wirsig-Wiechmann CR, Oka Y (2002) The terminal nerve ganglion cells project to the olfactory mucosa in the dwarf gourami brain. Neuroscience Research 44: 337-341.

@Amano M, Oka Y, Yamanome T, Okuzawa K, Yamamori K (2002) Three GnRH systems in the brain and pituitary of a pleuronectiform fish, barfin flounder, Verasper moseri. Cell and Tissue Research 309: 323-329.

@Tsutsui H, Oka Y (2002) Slow removal of Na+ channel inactivation underlies the temporal filtering property in the teleost thalamic neurons. Journal of Physiology 539: 743-753.

@Oka Y (2002) GnRH peptide as a neuromodulator and its release mechanisms. In: "Monograph of Fish Neuroscience" (ed. by K. Uematsu, H. Ito, and Y. Oka), Koseisha-Koseikaku, Tokyo, pp. 160-177.

@Abe H, Oka Y (2002) Mechanisms of the modulation of pacemaker activity by GnRH peptides in the terminal nerve-GnRH neurons. Zoological Science 19: 111-128.

@Oka Y Abe H (2002) Physiology of GnRH neurons and modulation of their activities by GnRH. In: "Neuroplasticity, Development, and Steroid Hormone Action" (ed. by R. Handa, S. Hayashi, E. Terasawa, and M. Kawata), CRC Press, Boca Raton, 191-203.

@Tsutsui H, Wolf AM, Knopfel T, Oka Y (2001) Imaging postsynaptic activities of teleost thalamic neurons at single cell resolution using a voltage-sensitive dye. Neuroscience Letters 312: 17-20.

@Kho KH, Tanimoto S, Inaba K, Oka Y, Morisawa M (2001) Transmembrane cell signaling for the initiation of trout sperm motility: roles of ion channels and membrane hyperpolarization for cyclic AMP synthesis. Zoological Science 18: 919-928.

@Tsutsui H, Yamamoto N, Ito H, Oka Y (2001) Encoding of different aspects of afferent activities by two types of cells in the corpus glomerulosum of a teleost brain. Journal of Neurophysiology 85: 1167-1177.

@Ishizaki M, Oka Y (2001) Amperometric recording of gonadotropin-releasing hormone (GnRH) release activity in the pituitary of the dwarf gourami (teleost) brain-pituitary slices. Neuroscience Letters 299: 121-124.

@Tsutsui H, Oka Y (2001) Effects of characteristic dendritic tip geometry on the electrical properties of teleost thalamic neurons. Journal of Neurophysiology 85: 2289-2292.

@Kim M, Kobayashi M, Oka Y, Amano M, Kawashima S, Aida K (2001) Effects of olfactory tract section on the immunohistochemical distribution of brain GnRH in the female goldfish Carassius auratus. Zoological Science 18: 241-248.

@Morisawa M, Izumi H, Yoshida M, Oka Y (2001) Cell signaling for activation of motility and chemotaxis in the sperm of Ciona. In: "The Biology of Ascidians" (ed. By H. Sawada, H. Yokosawa, and C.C. Lambert), Springer Verlag, Tokyo, 86-91.

@Abe H, Oka Y (2000) Modulation of pacemaker activity by salmon gonadotropin-releasing hormone (sGnRH) in terminal nerve (TN)-GnRH neurons. Journal of Neurophysiology 83: 3196-3200.

@Tsutsui H, Oka Y (2000) Light-sensitive voltage responses in the neurons of the cerebral ganglion of Ciona savignyi (Chordata: Ascidiacea). Biological Bulletin 198: 26-28.

@Oka Y (2000) Tropical fish brain as a model system for the neurobiological study of peptidergic neurons. Biophysics 40: 254-257.

@Izumi H, Marian T, Inaba K, Oka Y, Morisawa M (1999) Membrane hyperpolarization by sperm-activating and -attracting factor (SAAF) increases camp level and activates sperm motility in the ascidian Ciona intestinalis. Developmental Biology 213: 246-256.

@Abe H, Oka Y (1999) Characterization of K+ currents underlying pacemaker potentials of fish gonadotropin-releasing hormone cells. Journal of Neurophysiology 81: 643-653.

@Oka Y (1999) Neurobiology of peptidergic neurons. Newsletter of Japan Society for Comparative Endocrinology. 92: 13-22.

@Tsutsui H, Yamamoto N, Ito H, Oka Y (1998) GnRH-immunoreactive neuronal system in the presumptive ancestral chordate, Ciona intestinalis (Ascidian). General and Comparative Endocrinology 112: 426-432.

@Amano M, Oka Y, Kitamura S, Ikuta, K, Aida K (1998) Ontogenic development of salmon GnRH and chicken GnRH-II systems in the brain of masu salmon. Cell and Tissue Research 293: 427-434.

@Yamamoto N, Parhar IS, Sawai N, Oka Y, Ito H (1998) Preoptic gonadotropin-releasing hormone (GnRH) neurons innervate the pituitary in teleosts. Neuroscience Research 31: 31-38.

@Yamamoto N, Oka Y, Yoshimoto M, Sawai N, Albert JS, Ito H (1998) Gonadotropin-releasing hormone neurons in the gourami midbrain: a double labeling study by immunocytochemistry and tracer injection. Neuroscience Letters 240: 50-52.

@Oka Y (1998) Physiology and morphology of gonadotropin-releasing hormone (GnRH) neuronal system of vertebrate brain. In: "Brain and Reproductionh(ed. by M. Ichikawa), Gakkai Shuppan Publishers, Tokyo, 69-96.

@Oka Y (1997) The gonadotropin-releasing hormone (GnRH) neuronal system of fish brain as a model system for the study of peptidergic neuromodulation. In: "GnRH neurons: genes to behaviorh(ed. by I.S. Parhar and Y. Sakuma), Brain Shuppan Publishers, Tokyo, 245-276

@Yamamoto N, Oka Y, Kawashima S (1997) Lesions of gonadotropin-releasing hormone (GnRH)-immunoreactive terminal nerve cells: effects on the reproductive behavior of male dwarf gouramis. Neuroendocrinology 65: 403-412.

@Oka Y (1996) Characterization of TTX-resistant persistent Na+ current underlying pacemaker potentials of fish gonadotropin-releasing hormone (GnRH) neurons. Journal of Neurophysiolology 75: 2397-2404.

@Oka Y (1995) Tetrodotoxin-resistant persistent Na+ current underlying pacemaker potentials of fish gonadotrophin-releasing hormone neurones. Journal of Physiology 482: 1-6.

@Yamamoto N, Oka Y, Amano M, Aida K, Hasegawa Y, Kawashima S (1995) Multiple gonadotropin-releasing hormone (GnRH) immunoreactive systems in the brain of the dwarf gourami, Colisa lalia: immunohistochemistry and radioimmunoassay. Journal of Comparative Neurology 355: 354-368.

@Kim M, Oka Y, Amano M, Kobayashi M, Aida K, Kawashima S (1995) Immunocytochemical localization of sGnRH and cGnRH-II in the goldfish brain. Journal of Comparative Neurology 356: 72-82.

@Oka Y (1995) Hormone and behavior (3) GnRH and behavior in fish. Clinical Neuroscience 13: 382-383.

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