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教員

教授 大橋 順 (Jun OHASHI)

略歴
2021年04月 東京大学大学院理学系研究科生物科学専攻教授
2014年10月 東京大学大学院理学系研究科生物科学専攻准教授
2011年10月 筑波大学医学医療系准教授(組織改編による名称変更)
2008年07月 筑波大学大学院人間総合科学研究科社会環境医学専攻准教授
2007年04月 東京大学大学院医学系研究科人類遺伝学分野助教
2003年05月 米国コーネル大学分子生物学遺伝学研究分野文部科学省在外研究員
1999年09月 博士(保健学)学位取得 東京大学
1997年10月 東京大学大学院医学系研究科人類遺伝学分野助手
1997年10月 東京大学大学院医学系研究科国際保健学専攻研究生
1997年09月 東京大学大学院医学系研究科国際保健学専攻博士課程単位取得済退学
1995年03月 東京大学大学院医学系研究科国際保健学専攻修士課程修了
1993年03月 東京大学医学部保健学科卒業

大橋順 研究業績

Publication list (as of Nov 18, 2021)

Original article (English)

2021
213) Maharani N, Soetadji A, Utari A, Naka I, Ohashi J, Mexitalia M. Cytochrome b-245 alpha chain gene variants and arterial function in Indonesian short stature children. Cardiology Research (in press).
212) Isshiki M, Naka I, Kimura R, Nishida N, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R, Ohashi J (2021) Admixture with indigenous people helps local adaptation: admixture-enabled selection in Polynesians. BMC Ecology and Evolution 21: 179.
211) Kawamura R, Miyao S, Onuma H, Uchigata Y, Kawasaki E, Ohashi J, Shiraishi S, Nishida W, Yokomoto-Umakoshi M, Takata Y, Osawa H, Makino H. Recurrent hypoglycemia due to a high titer of insulin antibody in response to exogenous insulin administration in two cases of type 1 diabetes. Internal Medicine (in press).
210) Isshiki M, Watanabe Y, Ohashi J (2021) Geographic variation in the polygenic score of height in Japan. Human Genetics 140: 1097–1108.
209) Anzurez A, Naka I, Miki S, Hosoya-Nakayama K, Isshiki M, Watanabe Y, Nakamura-Hoshi M, Seki S, Matsumura T, Takano T, Onodera T, Adachi Y, Moriyama S, Terahara K, Tachikawa N, Yoshimura Y, Sasaki H, Horiuchi H, Miyata N, Miyazaki K, Koga M, Ikeuchi K, Nagai H, Saito M, Adachi E, Yotsuyanagi H, Kutsuna S, Kawashima A, Miyazato Y, Kinoshita N, Kouno C, Tanaka K, Takahashi Y, Suzuki T, Matano T, Ohashi J, Kawana-Tachikawa A (2021) Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-19. HLA 98: 37-42.
208) Nishida N, Sugiyama M, Ohashi J, Kawai Y, Khor SS, Nishina S, Yamasaki K, Yazaki H, Okudera K, Tamori A, Eguchi Y, Sakai A, Kakisaka K, Sawai H, Tsuchiura T, Ishikawa M, Hino K, Sumazaki R, Takikawa Y, Kanda T, Yokosuka O, Yatsuhashi H, Tokunaga K, Mizokami M (2021) Importance of HBsAg recognition by HLA molecules as revealed by responsiveness to different hepatitis B vaccines. Scientific Reports 11: 3703.
207) Mizuno F, Naka I, Ueda S, Ohashi J, Kurosaki K (2021) The number of SNPs required for distinguishing Japanese from other East Asians. Legal Medicine 49:101849.

2020
206) Watanabe Y, Isshiki M, Ohashi J (2020) Prefecture-level population structure of the Japanese based on SNP genotypes of 11,069 individuals. Journal of Human Genetics 66: 431-437.
205) Arayasongsak U, Naka I, Ohashi J, Patarapotikul J, Nuchnoi P, Kalambaheti T, Sa-Ngasang A, Chanama S, Chaorattanakawee S (2020) Genetic association study of interferon lambda 3, CD27, and human leukocyte antigen-DPB1 with dengue severity in Thailand. BMC Infectious Diseases 20: 948.
204) Miotto O, Sekihara M, Tachibana S, Yamauchi M, Pearson RD, Amato R, Gonçalves S, Mehra S, Noviyanti R, Marfurt J, Auburn S, Price RN, Mueller I, Ikeda M, Mori T, Hirai M, Tavul L, Hetzel M, Laman M, Barry A, Ringwald P, Ohashi J, Hombhanje F, Kwiatkowski DP, Mita T (2020) Emergence of artemisinin-resistance Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea. PLoS Pathogens 16: e1009133.
203) Toyoda M, Kamori D, Tan TS, Goebuchi K, Ohashi J, Carlson J, Kawana-Tachikawa A, Gatanaga H, Oka S, Pizzato M, Ueno T (2020) Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals. Scientific Reports 10: 19416.
202) Okamura K, Abe Y, Naka I, Ohashi J, Yagami A, Matsunaga K, Kobayashi Y, Fukai K, Tanemura A, Katayama I, Masui Y, Ito A, Yamashita T, Nagai H, Nishigori C, Oiso N, Aoyama Y, Araki Y, Saito T, Hayashi M, Hozumi Y, Suzuki T (2020) Genome-wide association study identifies CDH13 as a susceptibility gene for rhododendrol-induced leukoderma. Pigment Cell and Melanoma Research 33: 826-833.
201) Liu X, Kosugi S, Koide R, Kawamura Y, Ito J, Miura H, Matoba N, Matsuzaki M, Fujita M, Kamada AJ, Nakagawa H, Tamiya G, Matsuda K, Murakami Y, Kubo M, Aswad A, Sato K, Momozawa Y, Ohashi J, Terao C, Yoshikawa T, Parrish NF, Kamatani Y (2020) Endogenization and excision of human herpesvirus 6 in human genomes. PLoS Genetics 16: e1008915.
200) Yamamoto T, Hashimoto M, Nagatomi K, Nogami T, Sofue Y, Hayashi T, Ido Y, Yatsushiro S, Abe K, Kajimoto K, Tamari N, Awuor B, Sonye G, Kongere J, Munga S, Ohashi J, Oka H, Minakawa N, Kataoka M, Mita T (2020) Development of a quantitative, portable, and automated fluorescent blue-ray device-based malaria diagnostic equipment with an on-disc SiO2 nanofiber filter. Scientific Reports 10: 6585.
199) Kim J, Jeon S, Choi JP, Blazyte A, Jeon Y, Kim JI, Ohashi J, Tokunaga K, Sugano S, Fucharoen S, Al-Mulla F, Bhak J (2020) The origin and composition of Korean ethnicity analyzed by ancient and present-day genome sequences. Genome Biol Evol 12: 553-565.
198) Isshiki M, Naka I, Watanabe Y, Nishida N, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Eddie R, Ohtsuka R, Ohashi J (2020) Admixture and natural selection shaped genomes of an Austronesian-speaking population in the Solomon Islands. Scientific Reports 10: 6872.
197) Arayasongsak U, Naka I, Ohashi J, Patarapotikul J, Nuchnoi P, Kalambaheti T, Sa-Ngasang A, Chanama S (2020) Interferon lambda 1 is associated with dengue severity in Thailand. International Journal of Infectious Diseases 93: 121-125.

2019
196) Hang NTL, Hijikata M, Maeda S, Thuong PH, Ohashi J, Huan HV, Hoang NP, Miyabayashi A, Cuong VC, Seto S, Hung NV, Keicho N (2019) Whole genome sequencing, analyses of drug resistance-conferring mutations, and correlation with transmission of Mycobacterium tuberculosis carrying katG-S315T in Hanoi, Vietnam. Scientific Reports 9: 15354.
195) Watanabe Y, Naka I, Khor SS, Sawai H, Hitomi Y, Tokunaga K, Ohashi J, Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period. Scientific Reports (in press)
194) Onuma H, Kawamura R, Tabara Y, Yamashita M, Ohashi J, Kawasaki E, Imagawa A, Yamada Y, Chujo D, Takahashi K, Suehiro T, Takata Y, Osawa H, Makino H. Variants in the BACH2 and CLEC16A gene may be associated with susceptibility to insulin-triggered type 1 diabetes. Journal of Diabetes Investigation (in press)
193) Wah ST, Hananantachai H, Patarapotikul J, Naka I, Ohashi J, Nuchnoi P. microRNA-27a and microRNA-146a SNP in cerebral malaria. Molecular Genetics and Genomic Medicine (in press)


2018
192) Isshiki M, Naka I, Nishida N, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R, Ohashi J (2018) Association of an intronic SNP of the EFEMP1 gene with height in Tongans. Meta Gene 17: 172-176.
191) Ohashi J, Naka I, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R. Association study of CREBRF missense variant (rs373863828:G>A; p.Arg457Gln) with levels of serum lipid profile in the Pacific populations. Annals of Human Biology 45: 215-219.
190) Mita T, Hombhanje F, Takahashi N, Makoto S, Yamauchi M, Tsukahara T, Kaneko A, Endo H, Ohashi J. Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea. Scientific Reports 8: 5565.
189) Nishida N, Sugiyama M, Sawai H, Nishina S, Sakai A, Ohashi J, Khor SS, Kakisaka K, Tsuchiura T, Hino K, Sumazaki R, Takikawa Y, Murata K, Kanda T, Yokosuka O, Tokunaga K, Mizokami M (2018) Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine. Hepatology 68: 848–858.
188) Ikeda M, Kaneko M, Tachibana S, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Yamauchi M, Sekihara M, Hashimoto M, Katuro OT, Olia A, Obwoya PS, Auma MA, Anywar DA, Odongo-Aginya EI, Okello-Onen J, Hirai M, Ohashi J, Palacpac NMQ, Kataoka M, Tsuboi T, Kimura E, Horii T, Mita T. Detection of Plasmodium falciparum isolates with high survival rates in ex-vivo ring-stage survival assay (RSA) in Uganda. Emerging Infectious Diseases 24: 718-726.
187) Chaorattanakawee S, Nuchnoi P, Hananantachai H, Tumkosit U, Saunders D, Naka I, Ohashi J, Patarapotikul J (2018) Sequence variation in Plasmodium falciparum merozoite surface protein-2 is associated with virulence causing severe and cerebral malaria. PLoS ONE 13: e0190418.
186) Issiki M, Naka I, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Ohtsuka R, Ohashi J (2018) Mitochondrial DNA variations in Austronesian-speaking populations living in the New Georgia Islands, the Western Province of the Solomon Islands. Journal of Human Genetics 63: 101-104.

2017
185) Eriguchi Y, Kuwabara H, Inai A, Kawakubo Y, Nishimura F, Kakiuchi C, Tochigi M, Ohashi J, Aoki N, Kato K, Ishiura H, Mitsui J, Tsuji S, Doi K, Yoshimura J, Morishita S, Shimada T, Furukawa M, Umekage T, Sasaki T, Kasai K, Kano Y (2017) Identification of candidate genes involved in the etiology of sporadic Tourette Syndrome by exome sequencing. Neuropsychiatric Genetics 174: 712-723.
184) Nakayama K, Ohashi J, Watanabe K, Munkhtulga L, Iwamoto S (2017) Evidence for very recent positive selection in Mongolians. Molecular Biology and Evolution 34: 1936-1946.
183) Naka I, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ataka Y, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R, Ohashi J (2017) A missense variant, rs373863828-A (p.Arg457Gln), of CREBRF and body mass index in Oceanic populations. Journal of Human Genetics 62: 847-849.
182) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Eddie R, Kimura R, Nakazawa M, Ishida T, Ohtsuka R, Ohashi J (2017) Polymorphisms Associated with a Tropical Climate and Root Crop Diet Induce Susceptibility to Metabolic and Cardiovascular Diseases in Solomon Islands. PLoS ONE 12: e0172676.
181) Yasukochi Y, Naka I, Patarapotikul J, Hananantachai H, Ohashi J (2017) Evolution of Fseg/Cseg dimorphism in region III of Plasmodium falciparum eba-175 gene. Infection, Genetics and Evolution 49: 251–255.
180) Onuma H, Tabara Y, Kawamura R, Ohashi J, Nishida W, Takata Y, Ochi M, Nishimiya T, Ohyagi Y, Kawamoto R, Kohara K, Miki T, Osawa H (2017) Dual Effects of a RETN Single Nucleotide Polymorphism (SNP) at -420 on Plasma Resistin: Genotype and DNA Methylation. The Journal of Clinical Endocrinology & Metabolism 102: 884-892.
179) Yasukochi Y, Ohashi J (2017) Elucidating the origin of HLA-B*73 allelic lineage: Did modern humans benefit by archaic introgression? Immunogenetics 69: 63-67.
178) Kamori D, Hasan Z, Ohashi J, Kawana-Tachikawa A, Gatanaga H, Oka S, Ueno T (2017) Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection. Journal of Medical Virology 89: 123-129.

2016
177) Kawamura R, Tabara Y, Tsukada A, Igase M, Ohashi J, Yamada R, Takata Y, Kawamoto R, Saito I, Onuma H, Tanigawa T, Yamada K, Kato N, Ohyagi Y, Miki T, Kohara K, Osawa H (2016) A genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population. Physiological Genomics 48: 874–881.
176) Dang TN, Naka I, Sa-Ngasang A, Anantapreecha S, Wichukchinda N, Sawanpanyalert P, Patarapotikul P, Tsuchiya N, Ohashi J (2016) Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever. BMC Medical Genetics 17: 43.
175) Ohashi J, Naka I, Hananantachai H, Patarapotikul J (2016) Association of PECAM1/CD31 polymorphisms with cerebral malaria. International Journal of Molecular Epidemiology and Genetics 7: 87-94.
174) Nishida N, Ohashi J, Khor SS, Sugiyama M, Tsuchiura T, Sawai H, Hino K, Honda M, Kaneko S, Yatsuhashi H, Yokosuka O, Koike K, Kurosaki M, Izumi N, Korenaga M, Kang JH, Tanaka E, Taketomi A, Eguchi Y, Sakamoto N, Yamamoto K, Tamori A, Sakaida I, Hige S, Itoh Y, Mochida S, Mita E, Takikawa Y, Ide T, Hiasa Y, Kojima H, Yamamoto K, Nakamura M, Saji H, Sasazuki T, Kanto T, Tokunaga K, Mizokami M (2016) Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis. Scientific Reports 6: 24767.
173) Mita T, Culleton R, Takahashi N, Nakamura M, Tsukahara T, Hunja C, Win Z, Htike W, Marma A, Dysoley L, Ndounga M, Dzodzomenyo M, Akhwale W, Kobayashi J, Uemura H, Kaneko A, Hombhanje F, Ferreira M, Endo H, Ohashi J (2016) Little polymorphism at the K13 propeller locus in worldwide Plasmodium falciparum populations prior to the introduction of artemisinin combination therapies. Antimicrobial Agents and Chemotherapy 60: 3340-3347.
172) Liu X, Homma A, Sayadi J, Yang S, Ohashi J, Takumi T (2016) Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system. Scientific Reports 6: 19675.
171) Hamada J, Onuma H, Ochi F, Hirai H, Takemoto K, Miyoshi A, Matsushita M, Kadota Y, Ohashi J, Kawamura R, Takata Y, Nishida W, Hashida S, Ishii E, Osawa H (2016) Endoplasmic reticulum stress induced by tunicamycin increases resistin mRNA through the PERK-ATF4-CHOP pathway in THP-1 human monocytes. Journal of Diabetes Investigation 7: 312–323.

2015
170) Nishida N, Ohashi J, Sugiyama M, Tsuchiura T, Yamamoto K, Hino K, Honda M, Kaneko S, Yatsuhashi H, Koike K, Yokosuka O, Tanaka E, Taketomi A, Kurosaki M, Izumi N, Sakamoto N, Eguchi Y, Sasazuki T, Tokunaga K, Mizokami M (2015) Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese. Tissue Antigens 86: 406-412.
169) Yasukochi Y, Naka I, Patarapotikul J, Hananantachai H, Ohashi J (2015) Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum. Malaria Journal 14: 293.
168) Miyadera H, Ohashi J, Lernmark A, Kitamura T, Tokunaga K (2015) Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. The Journal of Clinical Investigation 125: 275-291.

2014
167) Nishida W, Nagata M, Imagawa A, Hanafusa T, Ohashi J, Takahashi K, Suehiro T, Yamada Y, Chujo D, Kawasaki E, Kawamura R, Onuma H, Osawa H, Makino H (2014) Insulin administration may trigger type 1 diabetes in Japanese type 2 diabetes patients with type 1 diabetes high-risk HLA class II and the insulin gene VNTR genotype. The Journal of Clinical Endocrinology & Metabolism 99: E1793-E1797.
166) Fujita A, Ishibe N, Yoshihara T, Ohashi J, Makino H, Ikeda M, Setoguchi H (2014) Rapid reversal of neuromuscular blockade by sugammadex after continuous infusion of rocuronium in patients with liver dysfunction undergoing hepatic surgery. Acta Anaesthesiologica Taiwanica 52: 54-58.
165) Dang TN, Naka I, Sa-Ngasang A, Anantapreecha S, Chanama S, Wichukchinda N, Sawanpanyalert P, Patarapotikul P, Tsuchiya N, Ohashi J (2014) A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome. BMC Medical Genetics 15: 58.
164) Naka I, Patarapotikul J, Hananantachai H, Imai H, Ohashi J (2014) Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria. Malaria Journal 13: 105.
163) Naka I, Patarapotikul J, Hananantachai H, Ohashi J (2014) Lack of association between BSG polymorphisms and cerebral malaria. Japanese Journal of Infectious Diseases 67: 432-435.
162) Honma H, Hirai M, Nakamura S, Hakimi H, Kawazu S, Palacpac NMQ, Hisaeda H, Matsuoka H, Kawai S, Endo H, Yasunaga T, Ohashi J, Mita T, Horii T, Furusawa M, Tanabe K (2014) Generation of rodent malaria parasites with a high mutation rate by destructing proofreading activity of DNA polymerase σ. DNA Research 21: 439-446.
161) Ohashi J, Suzuki Y, Naka I, Hananantachai H, Patarapotikul J (2014) Diversifying selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum in Thailand. PLoS ONE 9: e90522.
160) Sa-Ngasang A, Ohashi J, Naka I, Anantapreecha S, Sawanpanyalert P, Patarapotikul J. Association of IL1B -31C/T and IL1RA variable number of an 86-bp tandem repeat with Dengue Shock Syndrome in Thailand (2014) The Journal of Infectious Diseases 210: 138-145.
159) Nishida N, Sawai H, Kashiwase K, Minami M, Sugiyama M, Seto WK, Yuen MF, Posuwan N, Poovorawan Y, Ahn SH, Han KH, Matsuura K, Tanaka Y, Kurosaki M, Asahina Y, Izumi N, Kang JH, Hige S, Ide T, Yamamoto K, Sakaida I, Murawaki Y, Itoh Y, Tamori A, Orito E, Hiasa Y, Honda M, Kaneko S, Mita E, Suzuki K, Hino K, Tanaka E, Mochida S, Watanabe M, Eguchi Y, Masaki N, Murata K, Korenaga M, Mawatari Y, Ohashi J, Kawashima M, Tokunaga K, Mizokami M (2014) New susceptibility and resistance HLA-DP alleles to HBV-related diseases identified by a trans-ethnic association study in Asia. PLoS ONE 9: e86449.
158) Shiraishi S, Miyao S, Kikuchi N, Ochi K, Sato E, Ohashi J, Kawamura R, Osawa H, Makino H (2014) Effects of carbohydrate counting on glycemic control and quality of life in patients with type 1 diabetes: a pilot study. Diabetology International 5: 181-186.
157) Mita T, Ohashi J, Nakamura M, Endo H, Tanabe K (2014) Ordered accumulation of mutations conferring resistance to sulfadoxine-pyrimethamine in the Plasmodium falciparum parasite. The Journal of Infectious Diseases 209: 130-139.

2013
156) Naka I, Ohashi J, Kimura R, Inaoka T, Matsumura Y (2013) Association of ADRB2 polymorphism with triglyceride levels in Tongans. Lipids in Health and Disease 12: 110.
155) Naka I, Hikami K, Nakayama K, Koga M, Nishida N, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ataka Y, Ishida T, InaokaT, Iwamoto S, Matsumura Y, Ohtsuka R, Tsuchiya N, Ohashi J (2013) A functional SNP upstream of the beta-2 adrenergic receptor gene (ADRB2) is associated with obesity in Oceanic populations. International Journal of Obesity 37: 1204-1210.
154) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Eddie R, Kimura R, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ataka Y, Ohtsuka R, Ohashi J (2013) Hypertension Susceptibility Gene Prevalence in the Pacific Islands and Associations with Hypertension in Melanesia. Journal of Human Genetics 58: 142-149.
153) Noguchi S, Hijikata M, Hamano E, Matsushita I, Ito H, Ohashi J, Nagase T, Keicho N (2013) MxA transcripts with distinct first exons and modulation of gene expression levels by single-nucleotide polymorphisms in human bronchial epithelial cells. Immunogenetics 65: 107-114.
152) Onuma H, Tabara Y, Kawamura R, Ohashi J, Nishida W, Takata Y, Ochi M, Nishimiya T, Kawamoto R, Kohara K, Miki T, Osawa H (2013) Plasma resistin is associated with single nucleotide polymorphisms of a possible resistin receptor, the decorin gene, in the general Japanese population. Diabetes 62: 649-652.

2012
151) Japanese Archipelago Human Population Genetics Consortium (Consortium members: Jinam T, Nishida N, Hirai M, Kawamura S, Oota H, Umetsu K, Kimura R, Ohashi J, Tajima A, Yamamoto T, Tanabe H, Mano S, Suto Y, Kaname T, Naritomi K, Yanagi K, Niikawa N, Omoto K, Tokunaga K, Saitou N (2012) The history of human populations in the Japanese Archipelago inferred from genome-wide SNP data with a special reference to the Ainu and the Ryukyuan populations. Journal of Human Genetics 57: 787-795.
150) Kawashima M, Ohashi J, Nishida N, Tokunaga K (2012) Evolutionary analysis of classical HLA class I and II genes suggests that recent positive selection acted on DPB1*04:01 in Japanese population. PLoS ONE 7: e46806.
149) Onuma H, Tohyama M, Imagawa A, Hanafusa T, Kobayashi T, Kano Y, Ohashi J, Hashimoto K, Osawa H, Makino H (2012) High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome. The Journal of Clinical Endocrinology & Metabolism 97: E2277-E2281.
148) Furukawa H, Oka S, Shimada K, Sugii S, Ohashi J, Matsui T, Ikenaka T, Nakayama H, Hashimoto A, Takaoka H, Arinuma Y, Okazaki Y, Futami H, Komiya A, Fukui N, Nakamura T, Migita K, Suda A, Nagaoka S, Tsuchiya N, Tohma S (2012) Association of Human Leukocyte Antigen with Interstitial Lung Disease in Rheumatoid Arthritis: A Protective Role for Shared Epitope. PLoS One 7: e33133.
147) Hirayasu K, Ohashi J, Kashiwase K, Hananantachai H, Naka I, Ogawa A, Takanashi M, Satake M, Nakajima K, Parham P, Arase H, Tokunaga K, Patarapotikul J, Yabe T (2012) Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA. PLoS Pathogens 8: e1002565.
146) Naka I, Ohashi J, Kimura R, Furusawa T, Yamauchi T, Nakazawa M, Natsuhara K, Ataka Y, Nishida N, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R (2012) DRD4 VNTR polymorphism in Oceanic populations. Anthropological Science 120: 151-155.
145) Hijikata M, Shojima J, Matsushita I, Tokunaga K, Ohashi J, Hang NTL, Horie T, Sakurada S, Hoang NP, Thuong PH, Lien LT, Keicho N (2012) Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese. Human Genetics 131: 675-682.

2011
144) Kawamura R, Tabara Y, Onuma H, Kawamoto R, Ohashi J, Takata Y, Nishida W, Katsuhiko Kohara K, Makino H, Miki T, Osawa H (2011) A single-nucleotide polymorphism in the human THADA gene is associated with circulating resistin in the general Japanese population. Diabetology International 2: 190-196.
143) Kraisin S, Naka I, Patarapotikul J, Nantakomol D, Nuchnoi P, Hananantachai H, Tsuchiya N, Ohashi J (2011) Association of ADAMTS13 polymorphism with cerebral malaria. Malaria Journal 10: 366.
142) Mita T, Venkatesan M, Ohashi J, Culleton R, Takahashi N, Tsukahara T, Ndounga M, Dysoley L, Endo H, Hombhanje F, Ferreira MU, Plowe CV, Tanabe K (2011) Limited geographical origin and global spread of sulfadoxine-resistant dhps alleles in Plasmodium falciparum populations. The Journal of Infectious Diseases 204: 1980-1988.
141) Naka I, Nishida N, Ohashi J (2011) No evidence for strong recent positive selection favoring the 7 repeat allele of VNTR in the DRD4 gene. PLoS One 6: e24410.
140) Koga M, Kawasaki A, Ito I, Furuya T, Ohashi J, Kyogoku C, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N (2011) Cumulative Association of Eight Susceptibility Genes with Systemic Lupus Erythematosus in a Japanese Female Population. Journal of Human Genetics 56: 503-507.
139) Myles S, Lea RA, Ohashi J, Chambers GK, Weiss JG, Hardouin E, Engelken J, Macartney-Coxson DP, Eccles DA, Naka I, Kimura R, Inaoka T, Matsumura Y, Stoneking M (2011) Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans. BMC Medical Genetics 12: 10.
138) Hijikata M, Matsushita I, Tanaka G, Tsuchiya T, Ito H, Tokunaga K, Ohashi J, Homma S, Kobashi Y, Taguchi Y, Azuma A, Kudoh S, Keicho N (2011) Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis. Human Genetics 129: 117-128.
137) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Kimura R, Nakazawa M, Ishida T, Nishida N, Eddie R, Ohtsuka R, Ohashi J (2011) The serum leptin level and body mass index in Melanesian and Micronesian Solomon Islanders: Focus on genetic factors and urbanization. American Journal of Human Biology 23: 435-444.
136) Ohashi J, Naka I, Tsuchiya N (2011) The impact of natural selection on an ABCC11 SNP determining earwax type. Molecular Biology and Evolution 28: 849-857.

2010
135) Kawasaki A, Ito S, Furukawa H, Hayashi T, Goto D, Matsumoto I, Kusaoi M, Ohashi J, Graham RR, Matsuta K, Behrens TW, Tohma S, Takasaki Y, Hashimoto H, Sumida Tand, Tsuchiya N (2010) Association of TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study. Arthritis Research & Therapy 12: R174.
134) Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H (2010) The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels, and lower HOMA-IR in Japanese population. Journal of Human Genetics 55: 600-604.
133) Ridruechai C, Mahasirimongkol S, Phromjai J, Yanai H, Nishida N, Matsushita I, Ohashi J, Yamada N, Moolphate S, Summanapan S, Chuchottaworn C, Manosuthi W, Kantipong P, Kanitvittaya S, Sawanpanyalert P, Keicho N, Khusmith S, Tokunaga K. (2010) Association analysis of susceptibility candidate region on chromosome 5q31 for tuberculosis. Genes and Immunity 11: 416-422.
132) Onuma H, Tabara Y, Kawamura R, Tanaka T, Ohashi J, Nishida W, Takata Y, Ochi M, Yamada K, Kawamoto R, Kohara K, Miki T, Makino H, Osawa H (2010) A at Single Nucleotide Polymorphism-358 Is Required for G at -420 to Confer the Highest Plasma Resistin in the General Japanese Population. PLoS One 5(3): e9718.
131) Osawa H, Tabara Y, Ohashi J, Kawamura R, Onuma H, Makino H (2010) Is rs34861192 or rs1862513 a more promising variant for determining plasma resistin in an aged Japanese population? Diabetologia 53: 795-797.
130) Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Kawamoto M, Fujimoto M, Takehara K, Sato S, Hara M, Tsuchiya N (2010) Association of FAM167A (C8orf13) - BLK region with systemic sclerosis. Arthritis & Rheumatism 62: 890-895.
129) Nantakomol D, Chanprasert S, Soogarun S, Ohashi J, Nuchnoi P (2010) Affordable technology for enumeration of the absolute CD4 T-lymphocyte count by cell bead assay. LabMedicine 41: 423-428.
128) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Kimura R, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ataka Y, Nishida N, Tsuchiya N, Ohtsuka R, Ohashi J (2010) The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders. Human Genetics 127: 287-294.
127) Ishiguro H, Horiuchi Y, Ishikawa M, Koga M, Imai K, Suzuki Y, Morikawa M, Inada T, Watanabe Y, Takahashi M, Someya T, Ujike H, Iwata N, Ozaki N, Onaivi ES, Kunugi H, Sasaki T, Itokawa M, Arai M, Niizato K, Iritani S, Naka I, Ohashi J, Kakita A, Takahashi H, Nawa H, Arinami T (2010) Brain Cannabinoid CB2 Receptor in Schizophrenia. Biological Psychiatry 67: 974-982.

2009
126) HUGO Pan-Asian SNP Consortium, Abdulla MA, Ahmed I, Assawamakin A, Bhak J, Brahmachari SK, Calacal GC, Chaurasia A, Chen CH, Chen J, Chen YT, Chu J, Cutiongco-de la Paz EM, De Ungria MC, Delfin FC, Edo J, Fuchareon S, Ghang H, Gojobori T, Han J, Ho SF, Hoh BP, Huang W, Inoko H, Jha P, Jinam TA, Jin L, Jung J, Kangwanpong D, Kampuansai J, Kennedy GC, Khurana P, Kim HL, Kim K, Kim S, Kim WY, Kimm K, Kimura R, Koike T, Kulawonganunchai S, Kumar V, Lai PS, Lee JY, Lee S, Liu ET, Majumder PP, Mandapati KK, Marzuki S, Mitchell W, Mukerji M, Naritomi K, Ngamphiw C, Niikawa N, Nishida N, Oh B, Oh S, Ohashi J, Oka A, Ong R, Padilla CD, Palittapongarnpim P, Perdigon HB, Phipps ME, Png E, Sakaki Y, Salvador JM, Sandraling Y, Scaria V, Seielstad M, Sidek MR, Sinha A, Srikummool M, Sudoyo H, Sugano S, Suryadi H, Suzuki Y, Tabbada KA, Tan A, Tokunaga K, Tongsima S, Villamor LP, Wang E, Wang Y, Wang H, Wu JY, Xiao H, Xu S, Yang JO, Shugart YY, Yoo HS, Yuan W, Zhao G, Zilfalil BA; Indian Genome Variation Consortium (2009) Mapping human genetic history in Asia. Science 326: 1541-1545.
125) Naka I, Patarapotikul J, Tokunaga K, Hananantachai H, Tsuchiya N, Ohashi J (2009) A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population. Malaria Journal 8: 290.
124) Naka I, Nishida N, Patarapotikul J, Nuchnoi P, Tokunaga K, Hananantachai H, Tsuchiya N, Ohashi J (2009) Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria. Malaria Journal 8: 232.
123) Noranate N, Prugnolle F, Jouin H, Tall A, Marrama L, Sokhna C, Ekala MT, Guillotte M, Bischoff E, Bouchier C, Patarapotikul J, Ohashi J, Trape JF, Rogier C, Mercereau-Puijalon O (2009) Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting. BMC Microbiology 9: 219.
122) Makino H, Shimizu I, Murao S, Kondo S, TabaraY, Fujiyama M, Fujii Y, Takada Y, Nakai K, Izumi K, Ohashi J, Kawamura R, Yamauchi J, Takata Y, Nishida W, Hashiramoto M, Onuma H, Osawa H (2009) A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes. Endocrine Journal 56: 1049-1058.
121) Naka I, Patarapotikul J, Hananantachai H, Tokunaga K, Tsuchiya N, Ohashi J (2009) IFNGR1 polymorphisms in Thai malaria patients. Infection, Genetics and Evolution 9: 1406-1409.
120) Fujimoto A, Nishida N, Kimura R, Miyagawa T, Yuliwulandari R, Batubara L, Mustofa MS, Samakkarn U, Settheetham-Ishida W, Ishida T, Morishita Y, Tsunoda T, Tokunaga K, Ohashi J (2009) FGFR2 is associated with hair thickness in Asian populations. Journal of Human Genetics 54: 461-465.
119) Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Hikami K, Kawamoto M, Fujimoto M, Takehara K, Sato S, Hara M, Tsuchiya N (2009) Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population. Arthritis & Rheumatism 60: 1845-1850.
118) Ohashi J (2009) A practical case-control association test for detecting a susceptibility allele at a copy number variation locus. Journal of Human Genetics 54: 169-173.
117) Osawa H, Tabara Y, Kawamoto R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Miki T, Makino H, Kohara K (2009) PPARgamma Pro12Ala Pro/Pro and resistin SNP-420 G/G genotypes are synergistically associated with plasma resistin in the Japanese general population. Clinical Endocrinology 71: 341-345.
116) Nantakomol D, Imwong M, Soontarawirat I, Kotjanya D, Khakhai C, Ohashi J, Nuchnoi P (2009) The absolute counting of red cell-derived microparticles with red cell bead by flow rate based assay. Cytometry Part B: Clinical Cytometry 76B: 191-198.
115) Ito I, Kawasaki A, Ohashi J, Hayashi T, Matsumoto I, Ito S, Tsutsumi A, Hom G, Graham RR, Takasaki Y, Hashimoto H, Behrens TW, Sumida T, Tsuchiya N (2009) Replication of the Association between C8orf13-BLK Region and Systemic Lupus Erythematosus in a Japanese Population. Arthritis & Rheumatism 60: 553-558.
114) Mahasirimongkol S, Yanai H, Nishida N, Ridruechai C, Matsushita I, Ohashi J, Summanapan S, Yamada N, Moolphate S, Chuchotaworn C, Chaiprasert A, Manosuthi W, Kantipong P, Kanitwittaya S, Sura T, Khusmith S, Tokunaga K, Sawanpanyalert P, Keicho N (2009) Genome-wide SNP-based linkage analysis of tuberculosis in Thais. Genes and Immunity 10: 77-83.

2008
113) Kawasaki A, Ito I, Hikami K, Ohashi J, Hayashi T, Goto D, Matsumoto I, Ito S, Tsutsumi A, Koga M, Arinami T, Graham RR, Hom G, Takasaki Y, Hashimoto H, Behrens TW, Sumida T, Tsuchiya N (2008) Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of STAT1-STAT4 region. Arthritis Research & Therapy 10: R113.
112) Miyagawa T, Kawashima M, Nishida N, Ohashi J, Kimura R, Fujimoto A, Shimada M, Morishita S, Shigeta T, Lin L, Hong SC, Faraco J, Shin YK, Jeong JH, Okazaki Y, Tsuji S, Honda M, Honda Y, Mignot E, Tokunaga K (2008) Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Nature Genetics 40: 1324-1328.
111) Teeranaipong P, Ohashi J, Patarapotikul J, Kimura R, Nuchnoi P, Hananantachai H, Naka I, Putaporntip C, Jongwutiwes S, Tokunaga K (2008) A Functional SNP in the CR1 Promoter Region Contributes to Protection against Cerebral Malaria. The Journal of Infectious Diseases 198: 1880-1891.
110) Fujimoto A, Ohashi J, Nishida N, Miyagawa T, Morishita Y, Tsunoda T, Kimura R, Tokunaga K (2008) A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia. Human Genetics 124: 179-185.
109) Miyagawa T, Nishida N, Ohashi J, Kimura R, Fujimoto A, Kawashima M, Koike A, Sasaki T, Tanii H, Otowa T, Momose Y, Nakahara Y, Gotoh J, Okazaki Y, Tsuji S, Tokunaga K (2008) Appropriate data cleaning methods for genome-wide association study. Journal of Human Genetics 53: 886-893.
108) Shiota S, Tochigi M, Shimada H, Ohashi J, Kasai K, Kato N, Tokunaga K, Sasaki T (2008) Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population. Journal of Human Genetics 53: 929-935.
107) Kurashina K, Yamashita Y, Ueno T, Koinuma K, Ohashi J, Horie H, Miyakura Y, Hamada T, Haruta H, Hatanaka H, Soda M, Choi YL, Takada S, Yasuda Y, Nagai H, Mano H (2008) Chromosome copy number analysis in screening for prognosis-related genomic regions in colorectal carcinoma. Cancer Science 99: 1835-1840.
106) Kimura R, Ohashi J, Matsumura Y, Nakazawa M, Inaoka T, Ohtsuka R, Osawa M, Tokunaga K (2008) Gene Flow and Natural Selection in Oceanic Human Populations, Inferred from Genome-wide SNP Typing. Molecular Biology and Evolution 25: 1750-1761.
105) Nuchnoi P, Ohashi J, Naka I, Nacapunchai D, Tokunaga K, Nishida N, Patarapotikul J (2008) Linkage Disequilibrium Structure of the 5q31-33 Region in a Thai Population. Journal of Human Genetics 53: 850-856.
104) Naka I, Ohashi J, Nuchnoi P, Hananantachai H, Looareesuwan S, Tokunaga K ,Patarapotikul J (2008) Lack of association of the HbE variant with protection from cerebral malaria in Thailand. Biochemical Genetics 46: 708-711.
103) Hirayasu K, Ohashi J, Tanaka H, Kashiwase K, Ogawa A, Takanashi M, Satake M, Jia GJ, Chimge NO, Sideltseva EW, Tokunaga K, Yabe T (2008) Evidence for natural selection on leukocyte immunoglobulin-like receptors for HLA class I in Northeast Asians. American Journal of Human Genetics 82: 1075-1083.
102) Nuchnoi P, Ohashi J, Kimura R, Hananantachai H, Naka I, Krudsood S, Looareesuwan S, Tokunaga K, Patarapotikul J (2008) Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. Annals of Human Genetics72: 327-336.
101) Fujimoto A, Kimura R, Ohashi J, Omi K, Yuliwulandari R, Batubara L, Mustofa MS, Samakkarn U, Settheetham-Ishida W, Ishida T, Morishita Y, Furusawa T, Nakazawa M, Ohtsuka R, Tokunaga K (2008) A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness. Human Molecular Genetics 17: 835-843.
100) Murao S, Kondo S, Ohashi J, Fujii Y, Shimizu I, Fujiyama M, Ohno K, Takada Y, Nakai K, Yamane Y, Osawa H, Makino H (2008) Anti-thyroid peroxidase antibody, IA-2 antibody, and fasting C-peptide levels predict beta cell failure in patients with latent autoimmune diabetes in adults (LADA) -a five year follow-up of the Ehime study-. Diabetes Research and Clinical Practice 80: 114-121.
99) Kato C, Tochigi M, Ohashi J, Koishi S, Kawakubo Y, Yamamoto K, Matsumoto H, Hashimoto O, Kim S-Y, Watanabe K, Kano Y, Nanba E, Kato N, Sasaki T (2008) Association study of the 15q11-q13 maternal expression domain in Japanese autistic patients. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 147B: 1008-1012.
98) Osawa H, Yamada K, Tabara Y,Ochi M, Onuma H, Nishida W, Shimizu I, Kawamoto R, Fujii Y, Miki T, Ohashi J, Makino H (2008) The G/G genotype of a single nucleotide polymorphism at -1066 of c-Jun N-terminal kinase 1 gene (MAPK8) does not affect type 2 diabetes susceptibility despite the specific binding of AP2a. Clinical Endocrinology 69: 36-44.
97) Osawa H, Ochi M, Tabara Y, Kato K, Yamauchi J, Takata Y, Nishida W, Onuma H, Shimizu I, Fujii Y, Miki T, Ohashi J, Makino H (2008) Serum resistin is positively correlated with the accumulation of metabolic syndrome factors in type 2 diabetes. Clinical Endocrinology 69: 74-80.
96) Kato K, Osawa H, Ochi M, Kusunoki Y, Ebisui O, Ohno K, Ohashi J, Shimizu I, Fujii Y, Tanimoto M, Makino H (2008) Serum total and high molecular weight adiponectin is correlated with the severity of diabetic retinopathy and nephropathy. Clinical Endocrinology 68: 442-449.
95) Osawa H, Tabara Y, Kawano R, Ohashi J, Ochi M, Onuma H, Nishida W, Yamada K, Nakura J, Kohara K, Miki T, Makino H (2008) Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL, and high sensitivity CRP in the Japanese general population. Diabetes Care 30: 1501-1506.
94) Tochigi M, Kato C, Ohashi J, Koishi S, Kawakubo Y, Yamamoto K, Matsumoto H, Hashimoto O, Kim S-Y, Watanabe K, Kano Y, Nanba E, Kato N, Sasaki T (2008) No association between the ryanodine receptor 3 gene and autism in a Japanese population. Psychiatry and Clinical Neurosciencse 62: 341-344.
93) Kawasaki A, Kyogoku C, Ohashi J, Miyashita R, Hikami K, Kusaoi M, Tokunaga K, Takasaki Y, Hashimoto H, Behrens TW, Tsuchiya N (2008) Association of interferon regulatory factor 5 (IRF5) polymorphisms with systemic lupus erythematosus in Japanese: Support for a crucial role of intron 1 polymorphisms. Arthritis & Rheumatism 58: 826-834.
92) Shi L, Ogata S, Yu JK, Ohashi J, Yu L, Shi L, Sun H, Lin K, Huang XQ, Matsushita M, Horai S, Muramatsu M, Chu JY, Tokunaga K (2008) Distribution of HLA alleles and haplotypes in Jinuo and Wa populations in Southwest China. Human Immunology 69: 58-65.
91) Yamauchi J, Osawa H, Takasuka T, Ochi M, Murakami A, Nishida W, Onuma H, Takata Y, Tabara Y, Miki T, Ohashi J, Makino H (2008) Serum resistin is reduced by glucose and meal loading in healthy human subjects. Metabolism 57: 149-156.
90) Hoa BK, Hang NTL, Kashiwase K, Ohashi J, Lien LT, Horie T, Shojima J, Hijikata M, Sakurada S, Satake M, Tokunaga K, Sasazuki T, Keicho N (2008) HLA-A, B, C, DRB1 and DQB1 alleles and haplotypes in the Kinh population in Vietnam. Tissue Antigens 71: 127-134.

2007
89) Ohashi J, Naka I, Kimura R, Natsuhara K, Yamauchi T, Furusawa T, Nakazawa N, Ataka Y, Patarapotikul J, Nuchnoi P, Tokunaga K, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R (2007) FTO polymorphisms in Oceanic populations. Journal of Human Genetics 52: 1031-1035.
88) Suga T, Ishikawa A, Kohda M, Otsuka Y, Yamada S, Yamamoto N, Shibamoto Y, Ogawa Y, Nomura K, Sho K, Omura M, Sekiguchi K, Kikuchi Y, Michikawa Y, Noda S, Sagara M, Ohashi J, Yoshinaga S, Mizoe J, Tsujii H, Iwakawa M, Imai T (2007) Haplotype-based analysis of genes associated with risk of adverse skin reactions after radiotherapy in breast cancer patients. International Journal of Radiation Oncology Biology Physics 69: 685-693.
87) Ochi M, Osawa H, Hirota Y, Hara K, Tabara Y, Tokuyama Y, Shimizu I, Kanatsuka A, Fujii Y, Ohashi J, Miki T, Nakamura N, Kadowaki T, Itakura M, Kasuga M, Makino H (2007) Frequency of the G/G genotype of resistin single nucleotide polymorphism at -420 appears to be increased in younger onset type 2 diabetes. Diabetes 56: 2834-2838.
86) Naka I, Ohashi J, Patarapotikul J, Hananantachai H, Wilairatana P, Looareesuwan S, Tokunaga K (2007) The genotypes of GYPA and GYPB carrying the MNSs antigens are not associated with cerebral malaria. Journal of Human Genetics 52: 476-479.
85) Kimura R, Fujimoto A, Tokunaga K, Ohashi J (2007) A practical genome scan for population-specific strong selective sweeps that have reached fixation. PLoS One 2: e286.
84) Osawa H, Ochi M, Kato K, Yamauchi J, Nishida W, Takata Y, Kawamura R, Onuma H, Takasuka T, Shimizu I, Fujii Y, Ohashi J, Makino H (2007) Serum resistin is associated with the severity of microangiopathies in type 2 diabetes. Biochemical and Biophysical Research Communications 355: 342-346.
83) Hananantachai H, Patarapotikul J, Ohashi J, Naka I, Krudsood S, Looareesuwan S, Tokunaga K (2007) Significant association between TNF-a (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand. Tissue Antigens 69: 277-280.
82) Kawasaki A, Tsuchiya N, Ohashi J, Murakami Y, Fukazawa T, Kusaoi M, Morimoto S, Matsuta K, Hashimoto H, Takasaki Y, Tokunaga K (2007) Role of APRIL (TNFSF13) polymorphisms in the susceptibility to systemic lupus erythematosus in Japanese. Rheumatology 46: 776-782.
81) Tamura Y, Kunugi H, Ohashi J, Hohjoh H (2007) Epigenetic aberration of the human REELIN gene in psychiatric disorders. Molecular Psychiatry 12: 593-600.
80) Ogata S, Shi L, Matsushita M, Liang YU, Huang XQ, Lei SHI, Sun H, Ohashi J, Muramatsu M, Tokunaga K, Chu JY (2007) Polymorphisms of HLA genes in Maonan people in China. Tissue Antigens 69:154-160.
79) Choi YL, Tsukasaki K, O'neill MC, Yamada Y, Onimaru Y, Matsumoto K, Ohashi J, Yamashita Y, Tsutsumi S, Kaneda R, Takada S, Aburatani H, Kamihira S, Nakamura T, Tomonaga M, Mano H (2007) A genomic analysis of adult T-cell leukemia. Oncogene 26: 1245-1255.
78) Tochigi M, Zhang X, Ohashi J, Hibino H, Otowa T, Rogers M, Kato T, Okazaki Y, Kato N, Tokunaga K, Sasaki T (2007) Association study between the TNXB locus and schizophrenia in a Japanese population. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144: 305-309.

2006
77) Ohashi J, Naka I, Toyoda A, Takasu M, Tokunaga K, Ishida T, Sakaki Y, Hohjoh H (2006) Estimation of the species-specific mutation rates of the DRB1 locus in human and chimpanzee. Tissue Antigens 68: 427-431.
76) Dechkum N, Hananantachai H, Patarapotikul J, Ohashi J, Krudsood S, Looareesuwan S, Tokunaga K (2006) Monocyte Chemoattractant Protein 1 (MCP-1) Gene Polymorphism Is Not Associated with Severe and Cerebral Malaria in Thailand. Japanese Journal of Infectious Diseases 59: 239-244.
75) Tochigi M, Suga M, Ohashi J, Otowa T, Yamasue H, Kasai K, Kato T, Okazaki Y, Kato N, Sasaki T (2006) No association between the metabotropic glutamate receptor type 3 gene (GRM3) and schizophrenia in a Japanese population. Schizophrenia Research 88:260-264.
74) Tochigi M, Zhang X, Ohashi J, Hibino H, Otowa T, Rogers M, Kato T, Okazaki Y, Kato N, Tokunaga K, Sasaki T (2006) Association study of the dysbindin (DTNBP1) gene in schizophrenia from the Japanese population. Neuroscience Research 56: 154-158.
73) Hara K, Horikoshi M, Kitazato H, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Tobe K, Nagai R, Kadowaki T (2006) Hepatocyte Nuclear Factor-4a P2 Promoter Haplotypes Are Associated With Type 2 Diabetes in the Japanese Population. Diabetes 55: 1260-1264.
72) Jalloh A, van Thien H, Ferreira MU, Ohashi J, Matsuoka H, Kanbe T, Kikuchi A, Kawamoto F (2006) Sequence Variation in the T-Cell Epitopes of the Plasmodium falciparum Circumsporozoite Protein among Field Isolates Is Temporally Stable: a 5-Year Longitudinal Study in Southern Vietnam. Journal of Clinical Microbiology 44: 1229-1235.
71) Horikoshi M, Hara K, Ohashi J, Miyake K, Tokunaga K, Ito C, Kasuga M, Nagai R, Kadowaki T (2006) A Polymorphism in the AMPKa2 Subunit Gene Is Associated With Insulin Resistance and Type 2 Diabetes in the Japanese Population. Diabetes 55: 919-923.
70) Ohashi J, Naka I, Kimura R, Tokunaga K, Nakazawa M, Ataka Y, Ohtsuka R, Inaoka T, Matsumura Y (2006) HLA-DRB1 polymorphism on Ha’ano Island of the Kingdom of Tonga. Anthropological Science 114: 193-198.
69) Hirayasu K, Ohashi J, Kashiwase K, Takanashi M, Satake M, Tokunaga K, Yabe T. (2006) Long-term persistence of both functional and non-functional alleles at the leukocyte immunoglobulin-like receptor A3 (LILRA3) locus suggests balancing selection. Human Genetics 119: 436-443.
68) Ohashi J, Naka I, Kimura R, Tokunaga K, Yamauchi T, Natsuhara K, Furusawa T, Yamamoto R, Nakazawa M, Ishida T, Ohtsuka R. (2006) Polymorphisms in the ABO blood group gene in three populations in New Georgia Islands, Solomon Islands. Journal of Human Genetics 51: 407-411.
67) Ohashi J, Naka I, Tokunaga K, Inaoka T, Ataka Y, Nakazawa M, Matsumura Y, Ohtsuka R. (2006) Mitochondrial DNA variation suggests extensive gene flow from Polynesian ancestors to indigenous Melanesians in the northwestern Bismarck archipelago. American Journal of Physical Anthropology 130: 551-556.
66) Shi L, Xu SB, Ohashi J, Sun H, Yu JK, Huang XQ, Tao YF, Yu L, Horai S, Chu JY, Tokunaga K. (2006) HLA-A, HLA-B, and HLA-DRB1 alleles and haplotypes in Naxi and Han populations in southwestern China (Yunnan province). Tissue Antigens 67: 38-44.

2005
65) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Tangpukdee N, Looareesuwan S, Tokunaga K (2005) A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand. Malaria Journal 4:38.
64) Osawa H, Onuma H, Ochi M, Murakami A, Yamauchi J, Takasuka T, Tanabe F, Shimizu I, Kato K, Nishida W, Yamada K, Tabara Y, Yasukawa M, Fujii Y, Ohashi J, Miki T, Makino H (2005) Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes. Biochemical Biophysical and Research Communications 335: 596-602.
63) Nam MH, Hijikata M, Tuan le A, Lien LT, Shojima J, Horie T, Nakata K, Matsushita I, Ohashi J, Tokunaga K, Keicho N. (2005) Variations of the CFTR gene in the Hanoi-Vietnamese. American Journal of Medical Genetics A 136: 249-253.
62) Hara K, Horikoshi M, Kitazato H, Yamauchi T, Ito C, Noda M, Ohashi J, Froguel P, Tokunaga K, Nagai R, Kadowaki T. (2005) Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes. Diabetologia. 48: 1307-1314.
61) Zhang X, Tochigi M, Ohashi J, Maeda K, Kato T, Okazaki Y, Kato N, Tokunaga K, Sawa A, Sasaki T. (2005) Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population. Schizophrenia Research 79: 175-180.
60) Tanaka G, Matsushita I, Ohashi J, Tsuchiya N, Ikushima S, Oritsu M, Hijikata M, Nagata T, Yamamoto K, Tokunaga K, Keicho N (2005) Evaluation of microsatellite markers in association studies: a search for an immune-related susceptibility gene in sarcoidosis. Immunogenetics 56: 861-870.
59) Ohashi J, Clark AG (2005) Application of the stepwise focusing method to optimization of the cost-effectiveness of genome-wide association study with limited research budget for genotyping and phenotyping. Annals of Human Genetics 69:323-328
58) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Brittenham G, Looareesuwan S, Clark AG, Tokunaga K (2005) Strong linkage disequilibrium of a HbE variant with the (AT)9(T)5 repeat in the BP1 binding site upstream of the b-globin gene in Thai population. Journal of Human Genetics 50: 7-11.
57) Hananantachai H, Patarapotikul J, Ohashi J, Naka I, Looareesuwan S, Tokunaga K (2005) Polymorphisms of HLA-B and HLA-DRB1 genes in Thai malaria patients. Japanese Journal of Infectious Diseases 58: 25-28.

2004
56) Akesaka T, Lee SG, Ohashi J, Bannai M, Tsuchiya N, Yoon Y, Tokunaga K, Song K (2004) Comparative study of the haplotype structure and linkage disequilibrium of chromosome 1p36.2 region in the Korean and Japanese populations. Journal of Human Genetics 49: 603-609.
55) Hitomi Y, Tsuchiya N, Kawasaki A, Kyogoku C, Ohashi J, Suzuki T, Fukazawa T, Bejrachandra S, Siriboonrit U, Chandanayingyong D, Suthipinittharm P, Tsao BP, Hashimoto H, Honda ZI, Tokunaga K (2004) CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B. Human Molecular Genetics 13: 2907-2917.
54) Itoyama S, Keicho N, Quy T, Phi NC, Long HT, Ha LD, Ban VV, Ohashi J, Hijikata M, Matsushita I, Kawana A, Yanai H, Kirikae T, Kuratsuji T, Sasazuki T (2004) ACE1 Polymorphism and Progression of SARS. Biochemical Biophysical and Research Communications 323: 1124-1129.
53) Osawa H, Yamada K, Onuma H, Murakami A, Ochi M,Hiroko Kawata, Nishimiya T, Niiya T, Shimizu I, Nishida W, Hashiramoto M, Kanatsuka A, Fujii Y, Ohashi J, Makino M (2004) The G/G Genotype of a Resistin Single-Nucleotide Polymorphism at -420 Increases Type 2 Diabetes Mellitus Susceptibility by Inducing Promoter Activity through Specific Binding of Sp1/3. American Journal of Human Genetics 75: 678-686.
52) Murao S, Makino H, Kaino Y, Konoue E, Ohashi J, Kida K, Fujii Y, Shimizu I, Kawasaki E, Fujiyama M, Kondo S, Tanaka K, Tarumi Y, Seto I, Kato K, Ohno K, Ebisui O, Takada Y, Tanabe K, Takemoto K, Onuma H, Nishimiya T, Osawa H (2004) Differences in the Contribution of HLA-DR and -DQ Haplotypes to Susceptibility to Adult-Onset and Childhood-Onset Type 1 Diabetes in Japanese Patients. Diabetes 53: 2684-2690.
51) Kamio K, Matsushita I, Tanaka G, Ohashi J, Hijikata M, Nakata K, Tokunaga K, Azuma A, Kudoh S, Keicho N (2004) Direct determination of MUC5B promoter haplotypes based on the method of single-strand conformation polymorphism and their statistical estimation. Genomics 84: 613-622.
50) Sato-Takeda M, Ihn H, Ohashi J, Tsuchiya N, Ishikawa Y, Satake M, Arita H, Tamaki K, Hanaoka K, Tokunaga K, Yabe T (2004) The human histocompatibility leukocyte antigen (HLA) haplotype is associated with the onset of postherpetic neuralgia after herpes zoster. Pain 110: 329-336.
49) Araki J, Ohashi J, Muramatsu M (2004) Application of discordant sib-pair linkage analysis for mapping minor histocompatibility antigen loci in a novel graft-versus-host-disease model. Tissue Antigens 64: 243-250.
48) Ohki-Kaneda R, Ohashi J, Yamamoto K, Ueno S, Ota J, Choi YL, Koinuma K, Yamashita Y, Misawa Y, Fuse K, Ikeda U, Shimada K, Mano H (2004) Cardiac function-related gene expression profiles in human atrial myocytes. Biochemical Biophysical Research Communications 320: 1328-1336.
47) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Brittenham G, Looareesuwan S, Clark AG, Tokunaga K (2004) Extended linkage disequilibrium surrounding the hemoglobin E variant due to malarial selection. American Journal of Human Genetics 74: 1198-1208.
46) Tochigi M, Zhang X, Umekage T, Ohashi J, Kato C, Marui T, Otowa T, Hibino H, Otani T, Kohda K, Liu S, Kato N, Tokunaga K, Sasaki T (2004) Association of six polymorphisms of the NOTCH4 gene with schizophrenia in the Japanese population. American Journal of Medical Genetics 128B: 37-40.
45) Chu ZT, Tsuchiya N, Kyogoku C, Ohashi J, Qian YP, Xu SB, Mao CZ, Chu JY, Tokunaga K (2004) Association of Fcg receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: a common susceptibility gene in the Asian populations. Tissue Antigens 63: 21-27.
44) Choi YL, Makishima H, Ohashi J, Yamashita Y, Ohmine K, Ohki R, Wada T, Koinuma K, Ota J, Isobe Y, Ishida F, Ymauchi K, Oshimi K, Mano H (2004) DNA microarray analysis of natural killer cell-type lymphoproliferative disease of granular lymphocytes with purified CD3-CD56+ fractions. Leukemia 18: 556-565.
43) Ohashi J, Naka I, Ohtsuka R, Inaoka T, Ataka Y, Nakazawa M, Tokunaga K, Matsumura Y (2004) Molecular polymorphism of ABO blood group gene in Austronesian and Non-Austronesian populations in Oceania. Tissue Antigens 63: 355-361.

2003
42) Ochi M, Osawa H, Onuma H, Murakami A, Nishimiya T, Shimada F, Kato K, Shimizu I, Shishino K, Murase M, Fujii Y, Ohashi J, Makino H (2003) The absence of evidence for major effects of the frequent SNP +299G>A in the resistin gene on susceptibility to insulin resistance syndrome associated with Japanese type 2 diabetes. Diabetes Research and Clinical Practice 61: 191-198.
41) Ohashi J, Maruya E, Tokunaga K, Saji H (2003) Power of association test for detection minor histocompatibility gene causing graft-versus-host disease following bone marrow transplantation. Journal of Human Genetics 48: 502-507.
40) Ohashi J, Tokunaga K (2003) The power of genome-wide linkage disequilibrium (LD) testing using microsatellite markers. Journal of Human Genetics 48: 487-491.
39) Hohjoh H, Ohashi J, Takasu M, Nishioka T, Ishida T, Tokunaga K (2003) Recent divergence of the HLA-DRB1*04 allelic lineage from the DRB1*0701 lineage after the separation of the human and chimpanzee species. Immunogenetics 54: 856-861.
38) Tarasenko O, Ohashi J, Ataka Y, Inaoka T, Ohtsuka R, Tokunaga K (2003) HLA-DRB1 polymorphism of Balopa islanders in Papua New Guinea. Anthropological Science 111: 157-164.
37) Ataka Y, Ohtsuka R, Inaoka T, Kawabata M, Ohashi J, Matsushita M, Tokunaga K, Kano S, Suzuki M (2003) Variation in malaria endemicity in relation to microenvironmental conditions in the Admiralty Islands, Papua New Guinea. Asia-Pacific Journal of Public Health 13: 85-90.
36) Osawa H, Niiya T, Onuma H, Murakami A, Ochi M, Nishimiya T, Ogura T, Kato K, Shimizu I, Fujii Y, Ohashi J, Yamada K, Liang SJ, Manganiello VC, Fujita-Yamaguchi Y, Makino H (2003) Systematic search for single nucleotide polymorphisms (SNPs) in the 5’flanking region of the human phosphodiesterase 3B gene: absence of evidence for major effects of identified polymorphisms on susceptibility to Japanese type 2 diabetes. Molecular Genetics and Metabolism 79: 43-51.
35) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2003) A single nucleotide substitution from C to T at position -1055 in the IL-13 promoter is associated with protection from severe malaria in Thailand. Genes and Immunity 4: 528-531.
34) Naka I, Ohashi J, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2003) Genetic variants of b-globin gene in Thai malaria patients. Southeast Asian Journal of Tropical Medicine and Public Health 34: 29-31.
33) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, Naka I, Looareesuwan S, Tokunaga K (2003) CD36 polymorphism is associated with protection from cerebral malaria. American Journal of Human Genetics 72: 364-374.
32) Osawa H, Onuma H, Murakami A, Ochi M, Mishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H (2003) Systematic search for single nucleotide polymorphisms (SNPs) in the FOXC2 gene: The Absence of evidence for the association of three frequent SNPs and four common haplotypes with Japanese type 2 diabetes. Diabetes 52: 562-567.

2002
31) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, Naka I, Looareesuwan S, Tokunaga K (2002) Absence of Association between the Fcg receptor IIIA-176F/V Polymorphism and the Severity of Malaria in Thai. Japanese Journal of Infectious Diseases 55: 167-169.
30) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, Naka I, Looareesuwan S, Tokunaga K (2002) Fcg receptor IIA and IIIB polymorphisms are associated with susceptibility to cerebral malaria. Parasitology International 51: 361-366.
29) Tochigi M, Ohashi J, Umekage T, Koda K, Hibino H, Otowa T, Marui T, Masui K, Sugahara Y, Kanamori R, Juji T, Kato N, Tokunaga K, Sasaki T (2002) HLA-A specificities and its relation with season of birth in Japanese patients with schizophrenia. Neuroscience Letters 329: 201-204.
28) Ohashi J, Tokunaga K (2002) The expected power of genome-wide linkage disequilibrium testing using single nucleotide polymorphism markers for detecting a low-frequency disease variant. Annals of Human Genetics 66: 297-306.
27) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2002) Significant association of longer forms of CCTTT microsatellite repeat in inducible nitric oxide synthase (iNOS) promoter with severe malaria in Thailand. The Journal of Infectious Diseases 186: 578-581.
26) Sato M, Ohashi J, Tsuchiya N, Kashiwase K, Ishikawa Y, Arita H, HanaokaK, Tokunaga K, Yabe T (2002) Association of HLA-A*3303-B*4403-DRB1*1302 haplotype, but not of TNFa promoter and NKp30 polymorphism, with postherpetic neuralgia (PHN) in the Japanese population. Genes and Immunity 3: 477-481.
25) Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H (2002) Systematic search for single nucleotide polymorphisms in the resistin gene. The absence of evidence for the association of three identified single nucleotide polymorphisms with Japansese type 2 diabetes. Diabetes 51: 863-866.

2001
24) Osawa H, Ochi M, Nishimiya T, Onuma H, Nakamaru K, Murakami A, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H (2001) A systematic search for single nucleotide polymorphisms (SNPs) in the insulin receptor gene: Association of an sSNP with hyperlipidemia in Japanese type 2 diabetic subjects. Clinical Genetics 60: 479-481.
23) Ohashi J, Naka I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2001) Absence of association between the allele coding methionine at position 29 in the N-terminal domain of ICAM-1 (ICAM-1Kilifi) and severe malaria in the northwest of Thailand. Japanese Journal of Infectious Diseases 54: 114-116.
22) Sato M, Ohashi J, Tsuchiya N, Tadokoro K, Juji T, Hanaoka K, Tokunaga K, Yabe T (2001) Identification of novel single nucleotide substitutions in the NKp30 gene expressed in human natural killer cells. Tissue Antigens 58: 255-258.
21) Osawa H, Onuma H, Murakami A, Ochi M, Nishimiya T, Kato K, Shimizu I, Fujii Y, Ohashi J, Makino H (2001) Systematic search for single nucleotide polymorphisms in the Insulin gene: evidence for a high frequency of -23T>A in Japanese subjects. Biochemical and Biophysical Research Communications 286:451-455.
20) Ohashi J, Tokunaga K (2001) Power of genomewide association studies of complex disease genes: Statistical limitation of indirect approaches using SNP markers. Journal of Human Genetics 46: 478-482.
19) Ohashi J, Yamamoto S, Tsuchiya N, Hatta Y, Komata T, Matsushita M, Tokunaga K (2001) Comparison of statistical power between 2 × 2 allele frequency and allele positivity tables in case-control studies of complex disease genes. Annals of Human Genetics 65: 197-206.
18) Hananantachai H, Patarapotikul J, Looareesuwan S, Ohashi J, Naka I, Tokunaga K (2001) Lack of association of -308A/G TNFA promoter and 196R/M TNFR2 polymorphisms with disease severity in Thai adult malaria patients. American Journal of Medical Genetics 102: 391-392.
17) Lin M, Chu CC, Chang SL, Lee JH, Loo HH, Akaza T, Juji T, Ohashi J, Tokunaga K (2001) The origin of Minnan and Hakka, the so-called “Taiwanese”, inferred by HLA study. Tissue Antigens 57: 192-199.
16) Tarasenko O, Ohashi J, Kitaev M, Razorilova S, Ardiyants A, Kutukeev T, Alisherov A, Toktorgazieva K, Tokunaga K (2001) HLA-DRB1 gene polymorphism in the Kyrgyz population. MHC 8:40-46.

2000
15) Tarasenko O, Ohashi J, Kitaev M, Alisherov A, Tyurebaeva B, Kutukeev T, Tokunaga K (2000) Polymorphisms of HLA-A and -B genes in the Kyrgyz population. Anthropological Science 108:293-303.
14) Ohashi J, Tokunaga K (2000) Computer simulation analysis suggests weak balancing selection operative at the MICA locus. Hereditas 131:25-28.
13) Tsuchiya N, Komata T, Matsushita M, Ohashi J, Tokunaga K (2000) New single nucleotide polymorphisms in the coding region of human TNFR2. Genes & Immunity 1:501-503.
12) Wu MS, Tani K, Sugiyama H, Hibino H, Izawa K, Tanabe T, Nakazaki Y, Ohashi J, Hohjoh H, Iseki T, Tojo A, Nakamura Y, Tanioka Y, Tokunaga K, Asano S (2000) MHC (Major Histocompatibility Complex) -DRB genes and polymorphisms in Common Marmoset. Journal of Molecular Evolution 51:214-222.
11) Ohashi J, Tokunaga K (2000) Sojourn times and substitution rate at overdominant and linked neutral loci. Genetics 155:921-927.
10) Ohashi J, Yoshida M, Ohtsuka R, Nakazawa M, Juji T, Tokunaga K (2000) Analysis of HLA-DRB1 polymorphism in Gidra living in South New Guinea. Human Biology 72:337-347.
9) Shibue T, Tsuchiya N, Komata T, Matsushita M, Shiota M, Ohashi J, Wakui M, Matsuta K, Tokunaga K (2000) Tumor necrosis factor a 5’-flanking region, TNF receptor II and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis. Arthritis & Rheumatism 43:753-757.
8) Keicho N, Ohashi J, Tamiya G, Nakata K, Taguchi Y, Azuma A, Ohishi N, Emi M, Park MH, Inoko H, Tokunaga K, Kudoh S (2000) Fine localization of a major disease-susceptibility locus for diffuse panbronchiolitis. American Journal of Human Genetics 66:501-507.
7) Bannai M, Ohashi J, Harihara S, Mitomi Y, Takahashi Y, Juji T, Omoto K, Tokunaga K (2000) Analysis of HLA genes and haplotypes in Ainu (from Hokkaido, northern Japan) supports the premise that they decent from Upper Paleolithic populations of East Asia. Tissue Antigens 55:128-139.
6) Lin M, Chu CC, Lee HL, Chang SL, Ohashi J, Tokunaga K, Akaza T, Juji T (2000) Heterogeneity of Taiwan’s indigenous population: possible relation to prehistoric Mongoloid dispersals. Tissue Antigens 55: 1-9.

1999
5) Matsushita M, Tsuchiya N, Nakayama T, Ohashi J, Shibue T, Shiota M, Oka T, Yamane A, Tokunaga K (1999) Allele typing of human TNFA 5’-flanking region using PCR-PHFA (preferential homoduplex formation assay): linkage disequilibrium with HLA class I and class II genes in Japanese. Tissue Antigens 54: 478-484.
4) Hatta Y, Tsuchiya N, Ohashi J, Matsushita M, Fujiwara K, Hagiwara K, Juji T, Tokunaga K (1999) Association of Fcg receptor IIIB, but not of Fcg receptor IIA and IIIA, polymorphisms with systemic lupus erythematosus in Japanese. Genes and Immunity 1: 53-60.
3) Hohjoh H, Nakayama T, Ohashi J, Miyagawa T, Tanaka H, Akaza T, Honda Y, Juji T, and Tokunaga K (1999) Significant association of a single nucleotide polymorphism in the tumor necrosis factor-alpha (TNF-a) gene promoter with human narcolepsy. Tissue Antigens 54: 138-145.
2) Ohashi J, Tokunaga K (1999) Selecting contingency table in population-based association study: allele frequency or positivity? Journal of Human Genetics 44: 246-248.
1) Hatta Y, Ohashi J, Imanishi T, Kamiyama H, Iha M, Shimabukuro T, Ogawa A, Tanaka H, Akaza T, Gojobori T, Juji T, Tokunaga K (1999) HLA genes and haplotypes in Ryukyuan suggest recent gene flow to the Okinawa islands. Human Biology 71: 353-365.


Original article (Japanese)
1) 大橋 順 2012 Extended Haplotype Homozygosity (EHH)を用いる正の自然選択検出法の検出力比較. 統計数理 60: 317-325.

Review and book (English)
5) Tsuchiya N, Ohashi J (2015) Human immune system diversity and its implications in diseases. Journal of Human Genetics 60: 655-656.
4) Kimura R, Ohashi J (2008) Identifying Regions of the Human Genome that Exhibit Evidence for Positive Selection. Handbook of Human Molecular Evolution, 2 Volume Set. Cooper DN, Kehrer-Sawatzki eds. Wiley. 2008.
3) Tsuchiya N, Ohashi J, Tokunaga K (2002) Variations in immune response genes and their associations with multifactorial immune disorders. Immunological reviews 190: .169-181.
2) Tokunaga K, Ohashi J, Bannai M, Juji T (2001) Genetic Link between Asians and Native Americans: Evidence from HLA genes and haplotypes. Human Immunology 62:1001-1008.
1) Komatsu-Wakui M, Ohashi J, Tokunaga K, Ishikawa Y, Kashiwase K, Ando H, Shiina T, Geraghty DE, Inoko H, Juji T (2000) MIC-A polymorphism and a MIC-A-MIC-B null haplotype with~100-kb deletion. Major Histocompatibility Complex. Kasahara M (ed.) Springer. pp 480-486.


助教 針原 伸二 (Shinji HARIHARA)

略歴
1991年06月 東京大学理学部人類学教室助手
(現在 東京大学大学院理学系研究科生物科学専攻助手)
1990年04月 愛知県コロニー発達障害研究所研究員
1987年07月 筑波大学社会系助手
1987年03月 東京大学大学院理学系研究科博士課程修了
1981年03月 東京大学理学部生物学科卒業

研究テーマ
DNA多型からみた日本人の起源・DNAにみられる加齢現象

特任教員

特任助教 中 伊津美 (Izumi NAKA)

略歴
2021年05月 東京大学大学院理学系研究科生物科学専攻特任助教
2014年10月 東京大学大学院理学系研究科生物科学専攻特任研究員
2014年04月 筑波大学医学医療系研究員
2013年04月 日本学術振興会特別研究員(PD(DC2からの変更))
2013年03月 博士(医学)学位取得(筑波大学)
2012年04月 日本学術振興会特別研究員(DC2)
2009年04月 筑波大学大学院人間総合科学研究科生命システム医学専攻入学
2008年11月 筑波大学医学系支援室(~2012年3月)
2000年04月 東京大学大学院医学系研究科人類遺伝学分野技術補佐員(~2008年10月)

業績
英文原著論文

2021
62) Isshiki M, Naka I, Kimura R, Nishida N, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R, Ohashi J (2021) Admixture with indigenous people helps local adaptation: admixture-enabled selection in Polynesians. BMC Ecology and Evolution 21: 179.
61) Anzurez A, Naka I, Miki S, Hosoya-Nakayama K, Isshiki M, Watanabe Y, Nakamura-Hoshi M, Seki S, Matsumura T, Takano T, Onodera T, Adachi Y, Moriyama S, Terahara K, Tachikawa N, Yoshimura Y, Sasaki H, Horiuchi H, Miyata N, Miyazaki K, Koga M, Ikeuchi K, Nagai H, Saito M, Adachi E, Yotsuyanagi H, Kutsuna S, Kawashima A, Miyazato Y, Kinoshita N, Kouno C, Tanaka K, Takahashi Y, Suzuki T, Matano T, Ohashi J, Kawana-Tachikawa A (2021) Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-19. HLA 98: 37-42.
60) Mizuno F*, Naka I*, Ueda S, Ohashi J, Kurosaki K. The number of SNPs required for distinguishing Japanese from other East Asians. Legal Medicine 49:101849. *co-first authors

2020
59) Arayasongsak U, Naka I, Ohashi J, Patarapotikul J, Nuchnoi P, Kalambaheti T, Sa-Ngasang A, Chanama S, Chaorattanakawee S (2020) Genetic association study of interferon lambda 3, CD27, and human leukocyte antigen-DPB1 with dengue severity in Thailand. BMC Infectious Diseases 20: 948.
58) Isshiki M, Naka I, Watanabe Y, Nishida N, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Eddie R, Ohtsuka R, Ohashi J (2020) Admixture and natural selection shaped genomes of an Austronesian-speaking population in the Solomon Islands. Scientific Reports 10: 6872.
57) Arayasongsak U, Naka I, Ohashi J, Patarapotikul J, Nuchnoi P, Kalambaheti T, Sa-Ngasang A, Chanama S (2020) Interferon lambda 1 is associated with dengue severity in Thailand. International Journal of Infectious Diseases 93: 121-125.

2019
56) Watanabe Y, Naka I, Khor SS, Sawai H, Hitomi Y, Tokunaga K, Ohashi J, Analysis of whole Y-chromosome sequences reveals the Japanese population history in the Jomon period. Scientific Reports (in press)

2018
55) Isshiki M, Naka I, Nishida N, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R, Ohashi J (2018) Association of an intronic SNP of the EFEMP1 gene with height in Tongans. Meta Gene 17: 172-176.
54) Issiki M, Naka I, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Ohtsuka R, Ohashi J (2018) Mitochondrial DNA variations in Austronesian-speaking populations living in the New Georgia Islands, the Western Province of the Solomon Islands. Journal of Human Genetics 63: 101-104.
53) Ohashi J, Naka I, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R. Association study of CREBRF missense variant (rs373863828:G>A; p.Arg457Gln) with levels of serum lipid profile in the Pacific populations. Annals of Human Biology 45: 215-219.

2017
52) Issiki M, Naka I, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M, Ishida T, Ohtsuka R, Ohashi J. Mitochondrial DNA variations in Austronesian-speaking populations living in the New Georgia Islands, the Western Province ofthe Solomon Islands. Journal of Human Genetics 63: 101-104.
51) Naka I, Furusawa T, Kimura R, Natsuhara K, Yamauchi T, Nakazawa M, Ataka Y, Ishida T, Inaoka T, Matsumura Y,Ohtsuka R, Ohashi J. A missense variant, rs373863828-A (p.Arg457Gln), of CREBRF and body mass index in Oceanic populations. Journal of Human Genetics 62: 847-849.
50) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Eddie R, Kimura R, Nakazawa M, Ishida T, Ohtsuka R, Ohashi J (2017) Polymorphisms Associated with a Tropical Climate and Root Crop Diet Induce Susceptibility to Metabolic and Cardiovascular Diseases in Solomon Islands. PLoS ONE 12: e0172676.
49) Yasukochi Y, Naka I, Patarapotikul J, Hananantachai H, Ohashi J (2017) Evolution of Fseg/Cseg dimorphism in region III of Plasmodium falciparum eba-175 gene. Infection, Genetics and Evolution 49: 251-255.

2016
48) Dang TN, Naka I, Sa-Ngasang A, Anantapreecha S, Wichukchinda N, Sawanpanyalert P, Patarapotikul P, Tsuchiya N,Ohashi J (2016) Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever. BMC Medical Genetics 17: 43
47) Ohashi J, Naka I, Hananantachai H, Patarapotikul J. Association of PECAM1/CD31 polymorphisms with cerebral malaria. International Journal of Molecular Epidemiology and Genetics 7: 87-94.

2015
46) Yasukochi Y, Naka I, Hananantachai H, Patarapotikul J, Ohashi J (2015) Genetic evidence for contribution of human dispersal to the genetic diversity of EBA-175 in Plasmodium falciparum. Malaria Journal 14: 293.

2014
45) Dang TN, Naka I, Sa-Ngasang A, Anantapreecha S, Chanama S, Wichukchinda N, Sawanpanyalert P, Patarapotikul P,Tsuchiya N, Ohashi J (2014) A replication study confirms the association of GWAS-identified SNPs at MICB and PLCE1 in Thai patients with dengue shock syndrome. BMC Medical Genetics 15: 58.
44) Naka I, Patarapotikul J, Hananantachai H, Imai H, Ohashi J(2014)Association of the endothelial protein C receptor (PROCR) rs867186-G allele with protection from severe malaria. Malaria Journal 13:105 doi:10.1186/1475-2875-13-105.
43) Naka I, Patarapotikul J, Hananantachai H, Ohashi J(2014)Lack of Association between BSG Polymorphisms and Cerebral Malaria. Japanese Journal of Infectious Diseases 67(6):432-5.
42) Ohashi J, Suzuki Y, Naka I, Hananantachai H, Patarapotikul J(2014)Diversifying selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum in Thailand. PLoS ONE 9: e90522.
41) Sa-Ngasang A, Ohashi J, Naka I, Anantapreecha S, Sawanpanyalert P, Patarapotikul J(2014)Association of IL1B -31C/Tand IL1RA variable number of an 86-bp tandem repeat with Dengue Shock Syndrome in Thailand. The Journal of InfectiousDiseases 210(1):138-145.

2013
40) Naka I, Ohashi J, Kimura R, Inaoka T, Matsumura Y (2013) Association of ADRB2 polymorphism with triglyceride levelsinTongans. Lipids in Health and Disease 12: 110.
39) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Eddie R, Kimura R, Nakazawa M, Ishida T, Inaoka T, Matsumura Y,AtakaY,Ohtsuka R, Ohashi J (2013) Hypertension Susceptibility Gene Prevalence in the Pacific Islands and Associations with Hypertension in Melanesia. Journal of Human Genetics 58: 142-149.
38) Naka I, Hikami K, Nakayama K, Koga M, Nishida N, Kimura R, Furusawa T, Natsuhara K, Yamauchi T, Nakazawa M,AtakaY, Ishida T, Inaoka T, Iwamoto S, Matsumura Y, Ohtsuka R, Tsuchiya N, Ohashi J.(2013) A functional SNP upstream ofthe beta-2 adrenergic receptor gene (ADRB2) is associated with obesity in Oceanic populations. International Journal of Obesity 37(9):1204-10

2012
37) Yamaguchi K, Watanabe C, Kawaguchi A, Sato T, Naka I, Shindo M, Moromizato K, Aoki K, Ishida H, Kimura R. (2012)Association of melanocortin 1 receptor gene (MC1R) polymorphisms with skin reflectance and freckles in Japanese. J HumGenet.57(11):700-8.
36) Hirayasu K, Ohashi J, Kashiwase K, Hananantachai H, Naka I, Ogawa A, Takanashi M, Satake M, Nakajima K, Arase H,Tokunaga K, Patarapotikul J, Yabe T. (2012) Significant association of KIR2DL3-HLA-C1 combination with cerebral malariaand implications for co-evolution of KIR and HLA. PLoS Pathogens 8: e1002565.
35) Naka I, Ohashi J, Kimura R, Furusawa T, Yamauchi T, Nakazawa M, Natsuhara K, Ataka Y, Nishida N, Ishida T, Inaoka T,Matsumura Y, Ohtsuka R.(2012)DRD4 VNTR polymorphism in Oceanic populations. Anthropological Science 120(2): 151-155.
34) Kobayash K, Yuliwulandari R, Yanai H, Naka I, Lien L. T, Hang N. T. L, Hijikata M, Keicho N, Tokunaga K (2012)Association of TLR polymorphisms with development of tuberculosis in Indonesian females. Tissue Antigens 79, 190-197

2011
33) Kraisin S, Naka I, Patarapotikul J, Nantakomol D, Nuchnoi P, Hananantachai H, Tsuchiya N, Ohashi J (2011) Association of ADAMTS13 polymorphism with cerebral malaria. Malaria Journal. 10:366 doi:10.1186/1475-2875-10-366.
32) Naka I, Nishida N, Ohashi J (2011) No evidence for strong recent positive selection favoring the 7 repeat allele of VNTR in the DRD4 gene. PLoS ONE 6: e24410.
31) Myles S, Lea RA, Ohashi J, Chambers GK, Weiss JG, Hardouin E, Engelken J, Macartney-Coxson DP, Eccles DA, Naka I, Kimura R, Inaoka T, Matsumura Y, Stoneking M (2011) Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans. BMC Medical Genetics. 12: 10.
30) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Kimura R, Nakazawa M, Ishida T, Nishida N, Eddie R, Ohtsuka R, Ohashi J (2011) The Serum Leptin Level and Body Mass Index in Melanesian and Micronesian Solomon Islanders: Focus on Genetic Factors and Urbanization. American Journal of Human Biology. 23: 435-444.
29) Ohashi J, Naka I, Tsuchiya N (2011) The impact of natural selection on an ABCC11 SNP determining earwax type. Molecular Biology and Evolution 28: 849-857.

2010
28) Furusawa T, Naka I, Yamauchi T, Natsuhara K, Kimura R, Nakazawa M, Ishida T, Inaoka T, Matsumura Y, Ataka Y,NishidaN, Tsuchiya N, Ohtsuka R, Ohashi J (2010) The Q223R polymorphism in LEPR is associated with obesity in Pacific Islanders. Human Genetics 127: 287-294.
27) Ishiguro H, Horiuchi Y, Ishikawa M, Koga M, Imai K, Suzuki Y, Morikawa M, Inada T, Watanabe Y, Takahashi M, SomeyaT, Ujike H, Iwata N, Ozaki N, Onaivi ES, Kunugi H, Sasaki T, Itokawa M, Arai M, Niizato K, Iritani S,Naka I, Ohashi J, Kakita A,Takahashi H, Nawa H, Arinami T (2010) Brain Cannabinoid CB2 Receptor in Schizophrenia. Biological psychiatry 67: 974-982.

2009
26) Naka I, Patarapotikul J, Tokunaga K, Hananantachai H, Tsuchiya N, Ohashi J (2009) A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population. Malaria Journal 8: 290.
25) Naka I, Nishida N, Patarapotikul J, Nuchnoi P, Tokunaga K, Hananantachai H, Tsuchiya N, Ohashi J (2009) Identification of a haplotype block in the 5q31 cytokine gene cluster associated with the susceptibility to severe malaria. Malaria Journal 8:232.
24) Naka I, Patarapotikul J, Hananantachai H, Tokunaga K, Tsuchiya N, Ohashi J (2009) IFNGR1 polymorphisms in Thai malaria patients. Infection, Genetics and Evolution 9: 1406-1409.

2008
23) Teeranaipong P, Ohashi J, Patarapotikul J, Kimura R, Nuchnoi P, Hananantachai H, NAKA I, Putaporntip C, Jongwutiwes S,Tokunaga K (2008) A Functional SNP in the CR1 Promoter Region Contributes to Protection against Cerebral Malaria. The Journal of Infectious Diseases 198:1880-91
22) Nuchnoi P, Ohashi J, NAKA I, Nacapunchai D, Tokunaga K, Nishida N, Patarapotikul J (2008) Linkage Disequilibrium Structure of the 5q31-33 Region in a Thai Population. Journal of Human Genetics 53: 850-856.
21) NAKA I, Ohashi J, Nuchnoi P, Hananantachai H, Looareesuwan S, Tokunaga K ,Patarapotikul J. (2008) Lack of association of the HbE variant with protection from cerebral malaria in Thailand. Biochemical Genetics 46(11-12):708-11.
20) Nuchnoi P, Ohashi J, Kimura R, Hananantachai H, NAKA I, Krudsood S, Looareesuwan S, Tokunaga K, Patarapotikul J(2008) Significant association between TIM1 promoter polymorphisms and protection against cerebral malaria in Thailand. Annals of Human Genetics 72: 27-336.

2007
19) Ohashi J, NAKA I, Kimura R, Natsuhara K, Yamauchi T, Furusawa T, Nakazawa N, Ataka Y, Patarapotikul J, Nuchnoi P,Tokunaga K, Ishida T, Inaoka T, Matsumura Y, Ohtsuka R (2007) FTO polymorphisms in Oceanic populations. Journal of Human Genetics 52: 1031-1035.
18) NAKA I, Ohashi J, Patarapotikul J, Hananantachai H, Wilairatana P, Sornchai Looareesuwan S, Tokunaga K (2007) The genotypes of GYPA and GYPB carrying the MNSs antigens are not associated with cerebral malaria. Journal of Human Genetics 52: 476-479.
17) Hananantachai H, Patarapotikul J, Ohashi J, NAKA I, Krudsood S, Looareesuwan S, Tokunaga K (2007) Significant association between TNF-α (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand. Tissue Antigens 69: 277-280.

2006
16) Ohashi J, NAKA I, Toyoda A, Takasu M, Tokunaga K, Ishida T, Sakaki Y, Hohjoh H (2006) Estimation of the species-specific mutation rates of the DRB1 locus in human and chimpanzee. Tissue Antigens 68: 427-431.
15) Ohashi J, NAKA I, Kimura R, Tokunaga K, Nakazawa M, Ataka Y, Ohtsuka R, Inaoka T, Matsumura Y (2006) HLA-DRB1 polymorphism on Ha’ano Island of the Kingdom of Tonga. Anthropological Science 114: 193-198.
14) Ohashi J, NAKA I, Kimura R, Tokunaga K, Yamauchi T, Natsuhara K, Furusawa T, Yamamoto R, Nakazawa M, Ishida T,Ohtsuka R. (2006) Polymorphisms in the ABO blood group gene in three populations in New Georgia Islands, SolomonIslands. Journal of Human Genetics 51: 407-411.
13) Ohashi J, NAKA I, Tokunaga K, Inaoka T, Ataka Y, Nakazawa M, Matsumura Y, Ohtsuka R. (2006) Mitochondrial DNA variation suggests extensive gene flow from Polynesian ancestors to indigenous Melanesians in the northwestern Bismarck archipelago. American Journal of Physical Anthropology 130: 551-556.

2005
12) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Tangpukdee N, Looareesuwan S, Tokunaga K (2005) A functional polymorphism in the IL1B gene promoter, IL1B -31C>T, is not associated with cerebral malaria in Thailand. Malaria Journal 4:38.
11) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Brittenham G, Looareesuwan S, Clark AG, Tokunaga K (2005)Strong linkage disequilibrium of a HbE variant with the (AT)9(T)5 repeat in the BP1 binding site upstream of the beta-globingene in Thai population. Journal of Human Genetics 50: 7-11.
10) Hananantachai H, Patarapotikul J, Ohashi J, NAKA I, Looareesuwan S, Tokunaga K (2005) Polymorphisms of HLA-B and HLA-DRB1 genes in Thai malaria patients. Japanese Journal of Infectious Diseases 58: 25-28.

2004
9) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Brittenham G, Looareesuwan S, Clark AG, Tokunaga K (2004) Extended linkage disequilibrium surrounding the hemoglobin E variant due to malarial selection. American Journal of Human Genetics 74: 1198-1208.
8) Ohashi J, NAKA I, Ohtsuka R, Inaoka T, Ataka Y, Nakazawa M, Tokunaga K, Matsumura Y (2004) Molecular polymorphism of ABO blood group gene in Austronesian and Non-Austronesian populations in Oceania. Tissue Antigens 63:355-361.

2003
7) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2003) A single nucleotide substitution from C to T at position -1055 in the IL-13 promoter is associated with protection from severe malaria in Thailand. Genes and Immunity 4: 528-531.
6) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, NAKA I, Looareesuwan S, Tokunaga K (2003) CD36 polymorphismis associated with protection from cerebral malaria. American Journal of Human Genetics 72: 364-374.

2002
5) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, NAKA I, Looareesuwan S, Tokunaga K (2002) Absence of Associationbetween the Fcg receptor IIIA-176F/V Polymorphism and the Severity of Malaria in Thai. Japanese Journal of InfectiousDiseases 55: 167-169.
4) Omi K, Ohashi J, Patarapotikul J, Hananantachai H, NAKA I, Looareesuwan S, Tokunaga K (2002) Fcg receptor IIA and IIIB polymorphisms are associated with susceptibility to cerebral malaria. Parasitology International 51: 361-366.
3) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2002) Significant association of longerforms of CCTTT microsatellite repeat in inducible nitric oxide synthase (iNOS) promoter with severe malaria in Thailand.Journal of Infectious Diseases 186: 578-581.

2001
2) Ohashi J, NAKA I, Patarapotikul J, Hananantachai H, Looareesuwan S, Tokunaga K (2001) Absence of association between the allele coding methionine at position 29 in the N-terminal domain of ICAM-1 (ICAM-1Kilifi) and severe malaria in the northwest of Thailand. Japanese Journal of Infectious Diseases 54: 114-116.
1) Hananantachai H, Patarapotikul J, Looareesuwan S, Ohashi J, NAKA I, Tokunaga K (2001) Lack of association of -308A/G TNFA promoter and 196R/M TNFR2 polymorphisms with disease severity in Thai adult malaria patients. American Journal of Medical Genetics 102: 391-392.

総説
中 伊津美 2014 ADRB2肥満関連多型の起源 医学のあゆみ. Vol 249, No 11, pp1217-1219
中 伊津美 2014 オセアニア集団の肥満とADRB2遺伝子多型-ゲノム人類学的視点から. 医学のあゆみ. Vol 248, No 3, pp227-229


中伊津美、大橋順 (2015) 東京大学生命科学シンポジウム 優秀ポスター賞 
オセアニア集団における ADRB2 遺伝子多型と肥満との関連 -肥満リスクアリルはどこから来たのか-