Department of Biological Sciences, Graduate School of Science, The University of Tokyo

Department of Biological Sciences
Graduate School of Science
The University of Tokyo

Labs Inagaki Lab

JP

Core Division / Biology Inagaki Lab Molecular Genetics

Laboratory Website

Associate Professor Soichi Inagaki

Subject of research

  1. 1. Deciphering how epigenomic patterns are established and faithfully inherited
  2. 2. Revealing the roles of the epigenome in development and environmental responses
  3. 3. Unraveling the mechanisms that drive epigenomic diversification

From Epigenomes to Life’s Design and Diversity

Epigenetic information—such as DNA methylation and histone modifications—adds a crucial regulatory layer that shapes gene expression and chromosome behavior, ultimately determining the identity of cells and organisms. Remarkably, these epigenomic states can change dynamically in response to both internal and external cues.

Using plant systems as our primary model, we aim to elucidate how epigenomic landscapes are formed, maintained across cell divisions and generations, and remodeled when the environment changes. Our work is grounded in genome‑wide “epigenomics” approaches that capture these layers of information in one sweep, coupling cutting‑edge wet‑lab experiments with powerful computational analyses. By tracking epigenome dynamics under fluctuating conditions, we seek to understand how living organisms leverage epigenetic regulation to adapt and thrive. If you are eager to transform your own ideas into discovery and enjoy the thrill of solving biological puzzles, we invite you to join us.
  • Epigenomics in plants