In nature, plants adapt to diverse environmental stresses through intimate associations with mutualistic microbes, such as rhizobia and mycorrhizal fungi. While the roles of these well-characterized mutualists have been extensively studied, plants also harbor a rich diversity of other microbial taxa whose functions remain largely unknown. Our laboratory seeks to uncover the potential contributions of these uncharacterized microbes to plant growth and health under fluctuating environmental conditions. Moreover, we aim to elucidate the plant adaptation mechanisms that are activated in response to complex plant–fungus–bacterium community interactions.