Research Highlights

 

A green algal species with three sex phenotypes that all mate in pairs identified in Sagami River water system of Japan

・Kohei Takahashi
・Tetsuya Higashiyama
・Hisayoshi Nozaki

[Press Release (in Japanese)]2021/07/13
Evolution. 2021 Jul 12.

 

Uncovering the Breeding History of Mibuna, a Traditional Vegetable of Kyoto!

・Hokuto Nakayama

[Press Release (in Japanese)]2021/06/02
Hortic Res. 2021 Jun 1

 

Memory, learning and decision making studied in worms: Researchers identify role of interneurons in food-seeking behavior

・Hirofumi Sato
・Yuichi Iino

[Press Release (in Japanese)]2021/05/26
Cell Rep. 2021 May 25

 

A study of Genetic characteristics and demographic history of RNF213, a risk gene for moyamoya disease

・Kae Koganebuchi
・Hiroki Oota

[Press Release (in Japanese)]2021/05/20
Ann Hum Genet. 2021 May 20

 

Genome study of Volvox species from Lake Biwa reveals how a new hermaphrodite species evolved from the ancestral dioecious species

・Kayoko Yamamoto
・Hisayoshi Nozaki

[Press Release (in Japanese)]2021/05/18
PNAS. 2021 May 25

 

Discovery of a conserved element in biological clocks -Involvement of calcium ion flux in the origin of clock-

・Naohiro Kon
・Takahiro Iwamoto
・Yoshitaka Fukada

[Press Release (in Japanese)]2021/05/01
Sci Adv. 2021 Apr 30

 

A new species of brittle star from Sagami Bay: overlooked biodiversity

・Masanori Okanishi
・Hisanori Kohtsuka

[Press Release (in Japanese)]2021/04/30
Zoological Science. 2021 Apr 29

 

Six papers published in the "Special Issue on the Yaponesian Genome Project" of Anthropological Science

・Hiroki Oota
・Kae Koganebuchi

[Press Release (in Japanese)]2021/04/09

 

Shade-tolerant plants are also tolerant to strong light in the fluctuating light

・Ichiro Terashima
・Mitsutoshi Matsuo
・Yoshihiro Suzuki
・Wataru Yamori
・Masaru Kono

[Press Release (in Japanese)]2021/04/08
Photosynth Res. 2021 Apr 4

 

Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping

・Akimitsu Higuchi
・Wataru Shihoya
・Masae Konno
・Hideki Kandori
・ Keiichi Inoue
・Osamu Nureki

[Press Release (in Japanese)]2021/03/31
Proc Natl Acad Sci U S A. 2021 Apr 6

 

Elucidation of a mechanism decreasing potency of antimalarial drugs

・Tomohisa Kitagawa
・Atsushi Matsumoto
・Ichiro Terashima
・Yukifumi Uesono

[Press Release (in Japanese)] 2021/03/27
J Med Chem. 2021 Mar 27.

 

How to make stomata depends on the lifestyle of a plant

・Yuki Doll
・Hiroyuki Koga
・Hirokazu Tsukaya

[Press Release (in Japanese)] 2021/03/30
Proc Natl Acad Sci U S A. 2021 Apr 6

 

Unifacial leaves use a phytohormone auxin to create a different axis along which they extend to be flat

・Akira Nukazuka
・Takahiro Yamaguchi
・Hirokazu Tsukaya

[Press Release (in Japanese)] 2021/03/23
Plant Physiol. 2021 Feb 23

 

X-ray free electron laser captured the light induced structural changes of channelrhodopsin

・Kazumasa Oda
・Tomohiro Nishizawa
・Osamu Nureki
・Minoru Kubo
・Takashi Nomura
・Eriko Nango
・So Iwata

[Press Release (in Japanese)] 2021/03/23
Elife. 2021 Mar 23

 

Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle

・Riku Egami
・Toshiya Kokaji
・Atsushi Hatano
・Shinya Kuroda

[Press Release (in Japanese)] 2021/03/20
iScience. 2021 Feb 20

 

Mechanism to coordinate overlapping transcription in the crowded genome

・Soichi Inagaki
・Satoyo Oya
・Tetsuji Kakutani

[Press Release (in Japanese)] 2021/03/01
Nat Plants. 2021 Mar 1

 

Avicularium Formation in a Bryozoan

・Haruka Yamaguchi
・Masato Hirose
・Mayuko Nakamura
・Sumio Udagawa
・Kohei Oguchi
・Junpei Shinji
・Hisanori Kohtsuka
・Toru Miura

[Press Release (in Japanese)] 2021/02/25
Zoological Science. 2021 Feb 25

 

The first record of fossil lateral arm plates of britles star from Japan

・Masanori Okanishi
・Shota Mitsui
・Ben Thuy

[Press Release (in Japanese)] 2021/02/17
Paleontological Research. 2021 Feb 17

 

ClC chloride channel contributes to taste-related behavior

・Chanhyun Park
・Shinji Kanda
・Yuichi Iino
・Hirofumi Kunitomo

[Press Release (in Japanese)] 2021/01/27
Elife. 2021 Jan 25

 

A novel virus vector technology has opened a door for studying molecular and cellular basis for neural circuit development in the rodent brain

・Kazuya Togashi
・Masato Tsuji
・Shunsuke Takeuchi
・Ryota Nakahama
・Kazuo Emoto

[Press Release (in Japanese)] 2020/12/09
Front. Cell. Neurosci. 2020 Dec 9

 

Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity

・Toshiya Kokaji
・Atsushi Hatano
・Yuki Ito
・Shinya Kuroda

[Press Release (in Japanese)] 2020/12/01
Sci Signal. 2020 Dec 1

 

Mechanisms to silence mobile DNA within the genome

・Taiko Kim
・Tetsuji Kakutani

[Press Release (in Japanese)] 2020/11/30
Nat Plants. 2020 Nov 30

 

Neural circuits for emergency in Drosophila larvae

・Natsuko Omamiuda-Ishikawa
・Moeka Sakai
・Kazuo Emoto

[Press Release (in Japanese)] 2020/11/02
PLoS Genet. 2020 Nov 2

 

Revealing the structure of a rhodopsin enzyme to hydrolyze cyclic nucleotides by light

・Tatsuya Ikuta
・Wataru Shihoya
・Takayuki Uchihashi
・Hideki Kandori
・Osamu Nureki

[Press Release (in Japanese)] 2020/09/01
Nat Commun. 2020 Nov 5

 

A microRNA reactivates neuronal regeneration

・Yasuko Kitatani
・Akane Tezuka
・Eri Hasegawa
・Satoyoshi Yanagi
・Kazuya Togashi
・Masato Tsuji
・Shu Kondo
・Jay Z Parrish
・Kazuo Emoto

[Press Release (in Japanese)] 2020/09/01
PLoS Genet. 2020 Aug 7

 

Different responses in individual cells give muscles more control: Variations dismissed as “noise” actually information

・Takumi Wada
・Ken-Ichi Hironaka
・Shinya Kuroda

[Press Release (in Japanese)] 2020/09/01
Cell Rep. 2020 Sep 1

 

A complete picture of the regulation of glucose metabolism in fat cells by insulin

・Satoshi Ohno
・Shinya Kuroda

[Press Release (in Japanese)] 2020/09/01
iScience. 2020 Aug 20

 

Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations

・Takashi Gakuhari
・Hiroki Oota

[Press Release (in Japanese)] 2020/08/25
Commun Biol. 2020 Aug 25

 

Unusual characters of a plant living with only one leaf

・Ayaka Kinoshita
・Hiroyuki Koga
・Hirokazu Tsukaya

[Press Release (in Japanese)] 2020/08/12
Front. Plant Sci.2020 Aug 12

 

Pattern of sucker development in cuttlefishes

・Ryosuke Kimbara
・Mayuko Nakamura
・小Kohei Oguchi
・Hisanori Kohtsuka
・Toru Miura

[Press Release (in Japanese)] 2020/08/24
Front Zool. 2020 Aug 24

 

Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies

・Kanae Demura
・Tsukasa Kusakizako
・Wataru Shihoya
・Masahiro Hiraizumi
・Akiyuki Taruno
・Osamu Nureki

[Press Release (in Japanese)] 2020/07/18
Sci Adv. 2020 Jul 17

 

Genomic insights of pentameral body evolution

・Naoki Irie
・Akihito Omori

[Press Release (in Japanese)] 2020/07/10
Commun Biol. 2020 Jul 10

 

Male neotenic reproductives accelerate additional differentiation of female reproductives by lowering JH titer in termites

・Kohei Oguchi
・Yasuhiro Sugime
・Hiroyuki Shimoji
・Yoshinobu Hayashi
・Toru Miura

[Press Release (in Japanese)] 2020/06/10
Sci Rep. 2020 Jun 10.

 

Adaptive reduction of male gamete number in the selfing plant Arabidopsis thaliana

・Takashi Tsuchimatsu
・Hiroyuki Kakui
・Misako Yamazaki
・Cindy Marona
・Hiroki Tsutsui
・Afif Hedhly
・Dazhe Meng
・Yutaka Sato
・Thomas Städler
・Ueli Grossniklaus
・Masahiro M Kanaoka
・Michael Lenhard
・Magnus Nordborg
・Kentaro K Shimizu

[Press Release (in Japanese)] 2020/06/08
Nat Commun. 2020 Jun 8.

 

Base editors for simultaneous introduction of C-to-T and A-to-G mutations

・Hideto Mori
・Soh Ishiguro
・Rina C Sakata
・Akihiko Kondo
・Keiji Nishida
・Masaru Tomita
・iroshi Nishimasu
・Osamu Nureki
・Hiroyuki Aburatani
・Nozomu Yachie

[Press Release (in Japanese)] 2020/06/02
Nat Biotechnol. 2020 Jun 2.

 

Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch.

・Shusaku Masuda
・Hikari Yoshitane
・Yoshitaka Fukada

[Press Release (in Japanese)] 2020/04/30
Proc Natl Acad Sci USA. 2020 Apr 30.

 

Oocyte chromosomes can be removed from zygotes wihtout using difficult techniques.

・Takaya Totsuka
・Miho Ohsugi

[Press Release (in Japanese)] 2020/04/16
Sci Rep. 2020 Apr 16.

 

Discovery of a molecular switch for career decision of plant cells

Takayuki Tamaki
Satoyo Oya
Makiko Naito
Mayuko Sato
Mayumi Wakazaki
Kiminori Toyooka
Hiroo Fukuda
Yuki Kondo

[Press Release (in Japanese)] 2020/04/22
Commun Biol. 2020 Apr 22.

 

Faster stomatal opening improves plant growth in fluctuating light

Haruki Kimura
Mimi Hashimoto-Sugimoto
Koh Iba
Ichiro Terashima
Wataru Yamori

[Press Release (in Japanese)] 2020/02/27
J Exp Bot. 2020 Feb 25.

 

LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection

Tomoko Takahashi
Yuko Nakano
Koji Onomoto
Mitsutoshi Yoneyama
Kumiko Ui-Tei

[Press Release (in Japanese)] 2019/12/09
Nucleic Acids Res. 2019 Dec 8.

 

Irradiating the whole plant improves photosynthetic efficiency

Shunji Shimadzu
Mitsunori Seo
Ichiro Terashima
Wataru Yamori

[Press Release (in Japanese)] 2019/11/28
Front. Plant Sci., 28 November 2019

 

A robust model for quantitative prediction of the silencing efficacy of wild-type and A-to-I edited miRNAs

Shen Tian
Goro Terai
Yoshiaki Kobayashi
Yasuaki Kimura
Hiroshi Abe
Kiyoshi Asai
Kumiko Ui-Tei

[Press Release (in Japanese)] 2019/11/02
RNA Biol. 2019 Nov 1:1-17.

 

Crystal structure of heliorhodopsin

Wataru Shihoya
Keiichi Inoue
Yuji Furutani
Takayuki Uchihashi
Hideki Kandori
Osamu Nureki

[Press Release (in Japanese)] 2019/09/26
Nature. 2019 Oct;574(7776):132-136.

 

Weevils deterred by complicated leaf shape: novel role of leaf shape in plant-hervibore interaction

Yumiko Higuchi
Atsushi Kawakita

[Press Release (in Japanese)] 2019/09/03
Nat Plants. 2019 Sep;5(9):959-964.

 

Starvation-sensing neurons generate a new type of behavioral maneuver

Moon Sun Jang
Yuichi Iino
Hirofumi Kunitomo

[Press Release (in Japanese)] 2019/08/27
Proc Natl Acad Sci U S A. 2019 Aug 27. pii: 201821716.

 

The Graph Splitting Method Resolves the Early Evolution of Genes

Motomu Matsui
Wataru Iwasaki

[Press Release (in Japanese)] 2019/08/20
Syst Biol. 2019 Jul 31. pii: syz049.

 

MOCCS2 analysis determines DNA sequences for circadian gene expression rhythms

Yoshitaka Fukada
Hikari Yoshitane
Yoshimasa Asano

[Press Release (in Japanese)] 2019/08/08
Communications Biology volume 2, Article number: 300 (2019)

 

It’s time to flower

Mitsutomo Abe

[Press Release (in Japanese)] 2019/04/03
Development 2019 146: dev171504

 

Elongation of soldier mandibles in termites: Linking environment with developmental mechanism

Yasuhiro Sugime
Kohei Oguchi
Hiroki Gotoh
Yoshinobu Hayashi
Masatoshi Matsunami
Shuji Shigenobu
Shigeyuki Koshikawa
Toru Miura

[Press Release (in Japanese)] 2019/03/04
Development doi: 10.1242/dev.171942 Published 4 March 2019

 

Regulatory mechanism of blue- and green-sensitive photoreceptor genes

Yohey OGAWA
Daisuke KOJIMA
Yoshitaka FUKADA

[Press Release (in Japanese)] 2019/02/12
PNAS published ahead of print February 14, 2019

 

A Rho-actin signaling pathway shapes cell wall boundaries in Arabidopsis xylem vessels

Yuki Sugiyama*
Yoshinobu Nagashima*
Mayumi Wakazaki
Mayuko Sato
Kiminori Toyooka
Hiroo Fukuda
Yoshihisa Oda
* equally contributed authors

[Press Release (in Japanese)] 2019/01/28
Nat Commun. 2019 Jan 28.

 

Metaepigenomic analysis reveals the unexplored diversity of DNA methylation in an environmental prokaryotic community

Satoshi Hiraoka
Yusuke Okazaki
Mizue Anda
Atsushi Toyoda
Shin-ichi Nakano
Wataru Iwasaki

[Press Release (in Japanese)] 2019/01/16
Nat Commun. 2019 Jan 11;10(1):159.

 

Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase

School of Engineering, The University of Tokyo
School of Science, The University of Tokyo
University of Toyama
RIKEN

[Press Release (in Japanese)] 2018/11/23
Science. 2018 Nov 22. pii: eaav0080.

 

Plasma membrane calcium pump mediates chemotaxis of ascidian sperm

Manabu Yoshida
Kaoru Yoshida
Kogiku Shiba
Kazuo Inaba

[Press Release (in Japanese)] 2018/11/09
Scientific Reports. volume 8, Article number: 16622 (2018)

 

Elucidation of “cutoff paradox” that long-chain alcohols lose their biological activities

Atsushi Matsumoto
Yukifumi Uesono

[Press Release (in Japanese)] 2018/10/29
Mol Pharmacol. 2018 Dec;94(6):1312-1320.

 

Discovery of enzyme for establishing two cotyledons of eudicots

RIKEN
Exploratory Research Center on Life and Living Systems
National Institute for Basic Biology
The University of Tokyo

[Press Release (in Japanese)] 2018/09/13
Development. 2018 Sep 12;145(17).

 

A subway map for diabetes: Insulin tracked through cell using new method combining database, experimental results

Kentaro Kawata
Atsushi Hatano
Katsuyuki Yugi
Shinya Kuroda

[Press Release (in Japanese)] 2018/09/11
iScience. Available online 10 September 2018.

 

Intelligent Image-Activated Cell Sorter

Keisuke Goda
Nao Nitta
Sotaro Uemura
Yutaka Yatomi

[Press Release (in Japanese)] 2018/08/28
Cell. Published:August 27, 2018

 

Temporal patterns of insulin selectively regulate multiple cellular in the rat liver

Shinya Kuroda
(Research led by Japan Science and Technology Agency)

[Press Release (in Japanese)] 2018/06/28
Cell Systems. 2018 Jun 27.

 

LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

Tomoko Takahashi
Kumiko Ui-Tei and others

[Press Release (in Japanese)] 2018/06/25
Nucleic Acids Res. 2018 Jun 25.

 

Structural analysis of zebrafish flagella reveals distinct roles of all PIH family proteins in axonemal dynein assembly

Hiroyuki Takeda and others
(Research led by Japan Science and Technology Agency)

[Press Release (in Japanese)] 2018/06/19
Elife. 2018 May 9;7. pii: e36979.

 

SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology

Sotaro Uemura and others
(Research led by RIKEN)

[Press Release (in Japanese)] 2018/06/06
Genome Biol. 2018 Jun 6;19(1):66.

 

Aphid pheromone gland: Oviparous female-specific development and sex-pheromone synthesis.

Toru Miura

[Press Release (in Japanese)] 2018/05/11
Zoological Letters 2018 4:9

 

Identification of a key gene that regulates early leaf development in rice

Yukiko Yasui
Hiro-Yuki Hirano

[Press Release (in Japanese)] 2018/04/26
PLoS Genet. 2018 Apr 23;14(4)

 

Movements in CRISPR-Cas9, a genome-editing tool, during the DNA cleavage process

Saki Osuka
Kazushi Isomura
Shohei Kajimoto
Tomotaka Komori
Hiroshi Nishimasu
Tomohiro Shima
Osamu Nureki
Sotaro Uemura

[Press Release (in Japanese)] 2018/04/17
EMBO J. 2018 Apr 12.

 

Tempuractis rinkai gen. et. sp. nov. collected from the rocky seashore at Misaki -The first evidence of obligate symbiosis between sea anemones and sponges-

Takato Izumi
Yuji Ise
Rei Ueshima

[Press Release (in Japanese)] 2018/04/09
Zoolog Sci. 2018 Apr;35(2):188-198

 

Newly discovered plant peptide regulates dehydration stress resistance -New development revealing dehydration stress responses in plants-

Fuminori Takahashi
Takehiro Suzuki
Yuriko Osakabe
Shigeyuki Betsuyaku
Yuki Kondo
Naoshi Dohmae
Hiroo Fukuda
Kazuko Yamaguchi-Shinozaki
Kazuo Shinozaki

[Press Release (in Japanese)] 2018/04/05
Nature 556, 235–238 (2018)

 

Three genes essential for cells to tell time

Kiyomichi Imamura
Hikari Yoshitane
Yoshitaka Fukada

[Press Release (in Japanese)] 2018/03/20
PNAS 2017 (DOI: 10.1073/pnas.1719298115)

 

A new species of basket star (Ophiuroidea) from Japan, for the first time in 106 years.

Masanori Okanishi

[Press Release (in Japanese)] 2018/03/09
Zootaxa. Vol 4392, No 2

 

A small blueprint of “Adam” – Next-generation genome sequencings resolve highly reduced sex chromosomal region “OSU” in initial transition to male

Takashi Hamaji
Hiroko Kawai-Toyooka
Atsushi Toyoda
Hisayoshi Nozaki

[Press Release (in Japanese)] 2018/03/08
Communications Biology. volume 1, Article number: 17 (2018)

 

Discovery of peptidergic neurons that show juvenile-specific burst firing

Chie Umatani
Yoshitaka Oka

[Press Release (in Japanese)] 2018/02/05
Endocrinology. 2018 Feb 1.

 Here, the latest research results that made the press release from the University of Tokyo are posted in 2017. In addition to these results, many other research results have been published at all times from the Department of Biological Sciences. Please refer to each lab web page for the latest publications.

Reaseach in 2017

Reaseach in 2016

Reaseach in 2015

Reaseach in 2014