We study genetic sequences using computers, mathematics, and algorithms. We like finding ancient and subtle relationships between sequences. For example, we are finding partial conservation of DNA that controls gene expression in diverse animals, such as humans, molluscs, arthropods, and even corals. These DNA sequences all control embryonic development, revealing “deep homology” across animals. We also hunt for fossils in genome sequences. Sometimes, DNA from a virus or other entity is inserted in a genome, and then decays by mutations. Finding such decayed “fossils” is the main way we can know about ancient viruses. To analyze sequences, we design probability calculations and efficient algorithms. The most important thing is critical thinking, rather than cargo culting popular and prestigious methods and jargon.