Department of Biological Sciences, Graduate School of Science, The University of Tokyo

Department of Biological Sciences
Graduate School of Science
The University of Tokyo

Labs Shirasu Lab

JP

Relevant Division, Interlocking faculties / Faculties in other universities, institutes Shirasu Lab Plant Immune Response/Echinoderm Biology/Malacology

Laboratory Website

Subject of research

  1. 1. Research on plant immunity receptors
  2. 2. Research on virulence in plant fungal pathogens
  3. 3. Research on parasitic plants

Understand plant immunity system and pathogen virulence system

Plants inherently possess strong defense (immune) capabilities against pathogens. By employing genomics, proteomics, and metabolomics approaches, we aim to isolate genes, proteins, and small chemical compounds involved in plant disease resistance and elucidate the plant immune system. Focusing on disease resistance signaling complexes and post-translational modifications of proteins that regulate the immune system, we will uncover dynamic regulatory mechanisms at the protein level. Additionally, using chemical genetics, we will obtain disease-resistant mutants and identify novel genes responsible for resistance. Furthermore, we will investigate the infection mechanisms of parasitic plants and the corresponding immune responses using genome-based approaches.
  • Haustorium, the infecting organ of a parasitic plant, invading the host Arabidopsis