Plants are born without deciding the exact number of organs they will produce in their lifetime, and they regulate their development and growth in response to the environment where they are rooted. While some cells regenerate lost organs to sustain their life, others choose to die for other cells. Our goal is to understand the survival strategies hidden within such unique life style of plants at the molecular levels. To achieve this goal, we study a wide range of plant species, focusing on epigenetic regulation and the biosynthesis and metabolic dynamics of biological polymers, such as RNA, proteins, and cell wall polymers, to investigate the diverse mechanisms governing gene expression and cell differentiation. We are also attempting to elucidate the interactions between organ primordia and between cells for the patterning of tissues and organs in plants using mathematical models. Let’s open the door to a new era of plant science together with us.