第1069回生物科学セミナーを開催します（2/10(水) 11:00～ 3号館412講義室）
第1069回生物科学セミナー
日時： 2月10日（水） 11:00-12:30
演者： Cesare Furlanello
（FBK – Bruno Kessler Foundation, Trento, Italy）
演題: Differential Network Analysis to identify stability and evolving structure of omics networks
We have introduced the Hamming-Ipsen-Mikhailov (HIM) distance as a new data science tool to quantify difference between networks with the same vertices, such as co-expression or meta-omics networks. In computational biology, the HIM distance can be used to evaluate local and structural changes together, e.g. revealing when progression of disease or development have stronger effects. At the same time, the distance is useful to study reproducibility of network reconstruction algorithms or to mine importance of clinical phenotypes. The method will be illustrated with examples with networks derived from developmental functional genomics, immuno-oncology and metagenomics. The HIM metrics comes with an open Source implementation within the R package nettols and its web analytics interface ReNette.
場所： 理学部 3号館 412号室
担当： 東京大学大学院理学系研究科・生物科学専攻・黒田研究室
